Guo XE - Search Results

1

Targeting tumor suppressor networks for cancer therapeutics.

Guo XE, Ngo B, Modrek AS, Lee WH. Guo XE, et al. Curr Drug Targets. 2014 Jan;15(1):2-16. doi: 10.2174/1389450114666140106095151. Curr Drug Targets. 2014. PMID: 24387338 Free PMC article.

2

Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors.

Zhu J, Chen H, Guo XE, Qiu XL, Hu CM, Chamberlin AR, Lee WH. Zhu J, et al. Among authors: guo xe. Eur J Med Chem. 2015;96:196-208. doi: 10.1016/j.ejmech.2015.04.021. Epub 2015 Apr 9. Eur J Med Chem. 2015. PMID: 25874343 Free PMC article.

3

Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism.

Hu CM, Zhu J, Guo XE, Chen W, Qiu XL, Ngo B, Chien R, Wang YV, Tsai CY, Wu G, Kim Y, Lopez R, Chamberlin AR, Lee EY, Lee WH. Hu CM, et al. Among authors: guo xe. Oncogene. 2015 Mar 5;34(10):1220-30. doi: 10.1038/onc.2014.67. Epub 2014 Mar 24. Oncogene. 2015. PMID: 24662830 Free PMC article.

4

Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation.

Guo XE, Chen CF, Wang DD, Modrek AS, Phan VH, Lee WH, Chen PL. Guo XE, et al. J Biol Chem. 2011 Nov 4;286(44):38783-38794. doi: 10.1074/jbc.M111.257956. Epub 2011 Sep 12. J Biol Chem. 2011. PMID: 21911497 Free PMC article.

5

Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression.

Ngo B, Hu CM, Guo XE, Ngo B, Wei R, Zhu J, Lee WH. Ngo B, et al. Among authors: guo xe. J Biol Chem. 2013 Nov 29;288(48):34403-13. doi: 10.1074/jbc.M113.490524. Epub 2013 Oct 15. J Biol Chem. 2013. PMID: 24129578 Free PMC article.

6

Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes.

Wang DD, Guo XE, Modrek AS, Chen CF, Chen PL, Lee WH. Wang DD, et al. Among authors: guo xe. J Biol Chem. 2014 Jun 13;289(24):16727-35. doi: 10.1074/jbc.M113.536540. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770417 Free PMC article.

7

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan.

Chen PL, Chen CF, Chen Y, Guo XE, Huang CK, Shew JY, Reddick RL, Wallace DC, Lee WH. Chen PL, et al. Among authors: guo xe. Oncogene. 2013 Feb 28;32(9):1193-201. doi: 10.1038/onc.2012.120. Epub 2012 May 7. Oncogene. 2013. PMID: 22562243 Free PMC article.

8

A novel role of the chromokinesin Kif4A in DNA damage response.

Wu G, Zhou L, Khidr L, Guo XE, Kim W, Lee YM, Krasieva T, Chen PL. Wu G, et al. Among authors: guo xe. Cell Cycle. 2008 Jul 1;7(13):2013-20. doi: 10.4161/cc.7.13.6130. Epub 2008 Apr 16. Cell Cycle. 2008. PMID: 18604178 Free PMC article.

9

Systemic chemotherapy improves outcome of hepatocellular carcinoma patients treated with transarterial chemoembolization.

Zhang WC, Du KY, Yu SF, Guo XE, Yu HX, Wu DY, Pan C, Zhang C, Wu J, Bian LF, Cao LP, Yu J. Zhang WC, et al. Among authors: guo xe. Hepatobiliary Pancreat Dis Int. 2024 Nov 16:S1499-3872(24)00159-0. doi: 10.1016/j.hbpd.2024.11.004. Online ahead of print. Hepatobiliary Pancreat Dis Int. 2024. PMID: 39632156

10

Evaluation of Dexamethasone-Eluting Cell-Seeded Constructs in a Preclinical Canine Model of Cartilage Repair.

Lee AJ, Gangi LR, Hu YJ, Dinescu AT, Guo XE, Bozynski CC, Kuroki K, Stoker AM, Marra KG, Ateshian GA, Cook JL, Hung CT. Lee AJ, et al. Among authors: guo xe. Tissue Eng Part A. 2024 Nov 28. doi: 10.1089/ten.tea.2024.0244. Online ahead of print. Tissue Eng Part A. 2024. PMID: 39607494

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