Dou Y - Search Results

1

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: dou y. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.

2

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.

Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Milne TA, et al. Among authors: dou y. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):749-54. doi: 10.1073/pnas.0408836102. Epub 2005 Jan 7. Proc Natl Acad Sci U S A. 2005. PMID: 15640349 Free PMC article.

3

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Dou Y, et al. Cell. 2005 Jun 17;121(6):873-85. doi: 10.1016/j.cell.2005.04.031. Cell. 2005. PMID: 15960975 Free article.

4

MLL associates specifically with a subset of transcriptionally active target genes.

Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. Milne TA, et al. Among authors: dou y. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14765-70. doi: 10.1073/pnas.0503630102. Epub 2005 Sep 30. Proc Natl Acad Sci U S A. 2005. PMID: 16199523 Free PMC article.

5

Regulation of MLL1 H3K4 methyltransferase activity by its core components.

Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Dou Y, et al. Nat Struct Mol Biol. 2006 Aug;13(8):713-9. doi: 10.1038/nsmb1128. Epub 2006 Jul 30. Nat Struct Mol Biol. 2006. PMID: 16878130

6

Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia.

Dou Y, Hess JL. Dou Y, et al. Int J Hematol. 2008 Jan;87(1):10-8. doi: 10.1007/s12185-007-0009-8. Epub 2007 Dec 4. Int J Hematol. 2008. PMID: 18224408

7

Dicer independent small RNAs associate with telomeric heterochromatin.

Cao F, Li X, Hiew S, Brady H, Liu Y, Dou Y. Cao F, et al. Among authors: dou y. RNA. 2009 Jul;15(7):1274-81. doi: 10.1261/rna.1423309. Epub 2009 May 21. RNA. 2009. PMID: 19460867 Free PMC article.

8

Two mammalian MOF complexes regulate transcription activation by distinct mechanisms.

Li X, Wu L, Corsa CA, Kunkel S, Dou Y. Li X, et al. Among authors: dou y. Mol Cell. 2009 Oct 23;36(2):290-301. doi: 10.1016/j.molcel.2009.07.031. Mol Cell. 2009. PMID: 19854137 Free PMC article.

9

Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.

Karatas H, Townsend EC, Bernard D, Dou Y, Wang S. Karatas H, et al. Among authors: dou y. J Med Chem. 2010 Jul 22;53(14):5179-85. doi: 10.1021/jm100139b. J Med Chem. 2010. PMID: 20575550 Free PMC article.

10

MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.

Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y. Li X, et al. Among authors: dou y. Mol Cell Biol. 2010 Nov;30(22):5335-47. doi: 10.1128/MCB.00350-10. Epub 2010 Sep 13. Mol Cell Biol. 2010. PMID: 20837706 Free PMC article.

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