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Biodistribution and molecular studies on orally administered nanoparticle-AON complexes encapsulated with alginate aiming at inducing dystrophin rescue in mdx mice.
Falzarano MS, Passarelli C, Bassi E, Fabris M, Perrone D, Sabatelli P, Maraldi NM, Donà S, Selvatici R, Bonaldo P, Sparnacci K, Laus M, Braghetta P, Rimessi P, Ferlini A. Falzarano MS, et al. Among authors: sparnacci k. Biomed Res Int. 2013;2013:527418. doi: 10.1155/2013/527418. Epub 2013 Dec 12. Biomed Res Int. 2013. PMID: 24392452 Free PMC article.
Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse.
Rimessi P, Sabatelli P, Fabris M, Braghetta P, Bassi E, Spitali P, Vattemi G, Tomelleri G, Mari L, Perrone D, Medici A, Neri M, Bovolenta M, Martoni E, Maraldi NM, Gualandi F, Merlini L, Ballestri M, Tondelli L, Sparnacci K, Bonaldo P, Caputo A, Laus M, Ferlini A. Rimessi P, et al. Among authors: sparnacci k. Mol Ther. 2009 May;17(5):820-7. doi: 10.1038/mt.2009.8. Epub 2009 Feb 24. Mol Ther. 2009. PMID: 19240694 Free PMC article.
Persistent dystrophin protein restoration 90 days after a course of intraperitoneally administered naked 2'OMePS AON and ZM2 NP-AON complexes in mdx mice.
Bassi E, Falzarano S, Fabris M, Gualandi F, Merlini L, Vattemi G, Perrone D, Marchesi E, Sabatelli P, Sparnacci K, Laus M, Bonaldo P, Rimessi P, Braghetta P, Ferlini A. Bassi E, et al. Among authors: sparnacci k. J Biomed Biotechnol. 2012;2012:897076. doi: 10.1155/2012/897076. Epub 2012 Oct 2. J Biomed Biotechnol. 2012. PMID: 23091362 Free PMC article.
Sulfonates-PMMA nanoparticles conjugates: a versatile system for multimodal application.
Monasterolo C, Ballestri M, Sotgiu G, Guerrini A, Dambruoso P, Sparnacci K, Laus M, De Cesare M, Pistone A, Beretta GL, Zunino F, Benfenati V, Varchi G. Monasterolo C, et al. Among authors: sparnacci k. Bioorg Med Chem. 2012 Nov 15;20(22):6640-7. doi: 10.1016/j.bmc.2012.09.023. Epub 2012 Sep 21. Bioorg Med Chem. 2012. PMID: 23043726
A new facile synthesis of tertiary dithioesters.
Alberti A, Benaglia M, Laus M, Sparnacci K. Alberti A, et al. Among authors: sparnacci k. J Org Chem. 2002 Nov 1;67(22):7911-4. doi: 10.1021/jo026162q. J Org Chem. 2002. PMID: 12398529
52 results