Konkol LC - Search Results

1

Towards the Total Synthesis of Marineosin A: Construction of the Macrocyclic Pyrrole and an Advanced, Functionalized Spiroaminal Model.

Aldrich LN, Berry CB, Bates BS, Konkol LC, So M, Lindsley CW. Aldrich LN, et al. Among authors: konkol lc. European J Org Chem. 2013 Jul 1;2013(20):10.1002/ejoc.201300643. doi: 10.1002/ejoc.201300643. European J Org Chem. 2013. PMID: 24415906 Free PMC article.

2

Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation.

Panarese JD, Konkol LC, Berry CB, Bates BS, Aldrich LN, Lindsley CW. Panarese JD, et al. Among authors: konkol lc. Tetrahedron Lett. 2013 May 1;54(18):2231-2234. doi: 10.1016/j.tetlet.2013.02.059. Tetrahedron Lett. 2013. PMID: 23606772 Free PMC article.

3

A General, Enantioselective Synthesis of 1-Azabicyclo[m.n.0]alkane Ring Systems.

Senter TJ, Schulte ML, Konkol LC, Wadzinski TE, Lindsley CW. Senter TJ, et al. Among authors: konkol lc. Tetrahedron Lett. 2013 Mar 27;54(13):1645-1648. doi: 10.1016/j.tetlet.2013.01.041. Tetrahedron Lett. 2013. PMID: 23459400 Free PMC article.

4

Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents.

Engers JL, Rodriguez AL, Konkol LC, Morrison RD, Thompson AD, Byers FW, Blobaum AL, Chang S, Venable DF, Loch MT, Niswender CM, Daniels JS, Jones CK, Conn PJ, Lindsley CW, Emmitte KA. Engers JL, et al. Among authors: konkol lc. J Med Chem. 2015 Sep 24;58(18):7485-500. doi: 10.1021/acs.jmedchem.5b01005. Epub 2015 Sep 10. J Med Chem. 2015. PMID: 26335039 Free PMC article.

5

VU6005806/AZN-00016130, an advanced M₄ positive allosteric modulator (PAM) profiled as a potential preclinical development candidate.

Engers DW, Melancon BJ, Gregro AR, Bertron JL, Bollinger SR, Felts AS, Konkol LC, Wood MR, Bollinger KA, Luscombe VB, Rodriguez AL, Jones CK, Bubser M, Yohn SE, Wood MW, Brandon NJ, Dugan ME, Niswender CM, Conn PJ, Bridges TM, Lindsley CW. Engers DW, et al. Among authors: konkol lc. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1714-1718. doi: 10.1016/j.bmcl.2019.05.026. Epub 2019 May 16. Bioorg Med Chem Lett. 2019. PMID: 31113706

6

Enantioselective synthesis of metacycloprodigiosin via the "Wasserman pyrrole".

Vega MM, Crain DM, Konkol LC, Thomson RJ. Vega MM, et al. Among authors: konkol lc. Tetrahedron Lett. 2015 Jun 3;56(23):3228-3230. doi: 10.1016/j.tetlet.2014.12.075. Tetrahedron Lett. 2015. PMID: 26120213 Free PMC article.

7

Diastereoselective oxidative carbon-carbon bond formation via silyl bis-enol ethers.

Avetta CT Jr, Konkol LC, Taylor CN, Dugan KC, Stern CL, Thomson RJ. Avetta CT Jr, et al. Among authors: konkol lc. Org Lett. 2008 Dec 18;10(24):5621-4. doi: 10.1021/ol802516z. Org Lett. 2008. PMID: 19053737

8

Oxidative carbon-carbon bond formation via allyldimethylsilyl enol ethers.

Konkol LC, Jones BT, Thomson RJ. Konkol LC, et al. Org Lett. 2009 Dec 3;11(23):5550-3. doi: 10.1021/ol902400q. Org Lett. 2009. PMID: 19888716 Free PMC article.

9

Enantioselective synthesis of biphenols from 1,4-diketones by traceless central-to-axial chirality exchange.

Guo F, Konkol LC, Thomson RJ. Guo F, et al. Among authors: konkol lc. J Am Chem Soc. 2011 Jan 12;133(1):18-20. doi: 10.1021/ja108717r. Epub 2010 Dec 9. J Am Chem Soc. 2011. PMID: 21141997 Free PMC article.

10

Enantioselective total synthesis and studies into the configurational stability of bismurrayaquinone A.

Konkol LC, Guo F, Sarjeant AA, Thomson RJ. Konkol LC, et al. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9931-4. doi: 10.1002/anie.201104726. Epub 2011 Sep 7. Angew Chem Int Ed Engl. 2011. PMID: 21898740 Free PMC article.

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