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Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents.
Yamaguchi Y, Nishide K, Kato M, Hata Y, Mizumaki K, Kinoshita K, Nonobe Y, Tabata T, Sakamoto T, Kataoka N, Nakatani Y, Ichida F, Mori H, Fukurotani K, Inoue H, Nishida N. Yamaguchi Y, et al. Among authors: kinoshita k. Circ J. 2014;78(3):610-8. doi: 10.1253/circj.cj-13-1126. Epub 2014 Jan 11. Circ J. 2014. PMID: 24419801 Free article. Clinical Trial.
A590T mutation in KCNQ1 C-terminal helix D decreases IKs channel trafficking and function but not Yotiao interaction.
Kinoshita K, Komatsu T, Nishide K, Hata Y, Hisajima N, Takahashi H, Kimoto K, Aonuma K, Tsushima E, Tabata T, Yoshida T, Mori H, Nishida K, Yamaguchi Y, Ichida F, Fukurotani K, Inoue H, Nishida N. Kinoshita K, et al. J Mol Cell Cardiol. 2014 Jul;72:273-80. doi: 10.1016/j.yjmcc.2014.03.019. Epub 2014 Apr 5. J Mol Cell Cardiol. 2014. PMID: 24713462
2,496 results