Schmidt M - Search Results

1

Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo.

Cesana D, Ranzani M, Volpin M, Bartholomae C, Duros C, Artus A, Merella S, Benedicenti F, Sergi Sergi L, Sanvito F, Brombin C, Nonis A, Serio CD, Doglioni C, von Kalle C, Schmidt M, Cohen-Haguenauer O, Naldini L, Montini E. Cesana D, et al. Among authors: schmidt m. Mol Ther. 2014 Apr;22(4):774-85. doi: 10.1038/mt.2014.3. Epub 2014 Jan 20. Mol Ther. 2014. PMID: 24441399 Free PMC article.

2

Detection and direct genomic sequencing of multiple rare unknown flanking DNA in highly complex samples.

Schmidt M, Hoffmann G, Wissler M, Lemke N, Müssig A, Glimm H, Williams DA, Ragg S, Hesemann CU, von Kalle C. Schmidt M, et al. Hum Gene Ther. 2001 May 1;12(7):743-9. doi: 10.1089/104303401750148649. Hum Gene Ther. 2001. PMID: 11339891

3

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.

Woods NB, Muessig A, Schmidt M, Flygare J, Olsson K, Salmon P, Trono D, von Kalle C, Karlsson S. Woods NB, et al. Among authors: schmidt m. Blood. 2003 Feb 15;101(4):1284-9. doi: 10.1182/blood-2002-07-2238. Epub 2002 Oct 17. Blood. 2003. PMID: 12393514 Free article.

4

Molecular evidence of lentiviral vector-mediated gene transfer into human self-renewing, multi-potent, long-term NOD/SCID repopulating hematopoietic cells.

Ailles L, Schmidt M, Santoni de Sio FR, Glimm H, Cavalieri S, Bruno S, Piacibello W, Von Kalle C, Naldini L. Ailles L, et al. Among authors: schmidt m. Mol Ther. 2002 Nov;6(5):615-26. Mol Ther. 2002. PMID: 12409260 Free article.

5

Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34+ cord blood cells.

Leurs C, Jansen M, Pollok KE, Heinkelein M, Schmidt M, Wissler M, Lindemann D, Von Kalle C, Rethwilm A, Williams DA, Hanenberg H. Leurs C, et al. Among authors: schmidt m. Hum Gene Ther. 2003 Apr 10;14(6):509-19. doi: 10.1089/104303403764539305. Hum Gene Ther. 2003. PMID: 12718762

6

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences.

Baum C, von Kalle C, Staal FJ, Li Z, Fehse B, Schmidt M, Weerkamp F, Karlsson S, Wagemaker G, Williams DA. Baum C, et al. Among authors: schmidt m. Mol Ther. 2004 Jan;9(1):5-13. doi: 10.1016/j.ymthe.2003.10.013. Mol Ther. 2004. PMID: 14741772 Free article. Review.

7

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.

Kiem HP, Sellers S, Thomasson B, Morris JC, Tisdale JF, Horn PA, Hematti P, Adler R, Kuramoto K, Calmels B, Bonifacino A, Hu J, von Kalle C, Schmidt M, Sorrentino B, Nienhuis A, Blau CA, Andrews RG, Donahue RE, Dunbar CE. Kiem HP, et al. Among authors: schmidt m. Mol Ther. 2004 Mar;9(3):389-95. doi: 10.1016/j.ymthe.2003.12.006. Mol Ther. 2004. PMID: 15006605 Free article.

8

Stem cell clonality and genotoxicity in hematopoietic cells: gene activation side effects should be avoidable.

von Kalle C, Fehse B, Layh-Schmitt G, Schmidt M, Kelly P, Baum C. von Kalle C, et al. Among authors: schmidt m. Semin Hematol. 2004 Oct;41(4):303-18. doi: 10.1053/j.seminhematol.2004.07.007. Semin Hematol. 2004. PMID: 15508116 Review.

9

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

Modlich U, Kustikova OS, Schmidt M, Rudolph C, Meyer J, Li Z, Kamino K, von Neuhoff N, Schlegelberger B, Kuehlcke K, Bunting KD, Schmidt S, Deichmann A, von Kalle C, Fehse B, Baum C. Modlich U, et al. Among authors: schmidt m, schmidt s. Blood. 2005 Jun 1;105(11):4235-46. doi: 10.1182/blood-2004-11-4535. Epub 2005 Feb 15. Blood. 2005. PMID: 15713797 Free article.

10

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells.

Podsakoff GM, Engel BC, Carbonaro DA, Choi C, Smogorzewska EM, Bauer G, Selander D, Csik S, Wilson K, Betts MR, Koup RA, Nabel GJ, Bishop K, King S, Schmidt M, von Kalle C, Church JA, Kohn DB. Podsakoff GM, et al. Among authors: schmidt m. Mol Ther. 2005 Jul;12(1):77-86. doi: 10.1016/j.ymthe.2005.02.024. Mol Ther. 2005. PMID: 15963923 Free article.

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