Couttas TA - Search Results

1

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.

Couttas TA, Kain N, Daniels B, Lim XY, Shepherd C, Kril J, Pickford R, Li H, Garner B, Don AS. Couttas TA, et al. Acta Neuropathol Commun. 2014 Jan 23;2:9. doi: 10.1186/2051-5960-2-9. Acta Neuropathol Commun. 2014. PMID: 24456642 Free PMC article.

2

Re-configuration of sphingolipid metabolism by oncogenic transformation.

Don AS, Lim XY, Couttas TA. Don AS, et al. Among authors: couttas ta. Biomolecules. 2014 Mar 14;4(1):315-53. doi: 10.3390/biom4010315. Biomolecules. 2014. PMID: 24970218 Free PMC article. Review.

3

Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy.

Don AS, Hsiao JH, Bleasel JM, Couttas TA, Halliday GM, Kim WS. Don AS, et al. Among authors: couttas ta. Acta Neuropathol Commun. 2014 Oct 29;2:150. doi: 10.1186/s40478-014-0150-6. Acta Neuropathol Commun. 2014. PMID: 25358962 Free PMC article.

4

A three-step assay for ceramide synthase activity using a fluorescent substrate and HPLC.

Couttas TA, Lim XY, Don AS. Couttas TA, et al. Lipids. 2015 Jan;50(1):101-9. doi: 10.1007/s11745-014-3969-5. Epub 2014 Nov 18. Lipids. 2015. PMID: 25403920

5

Fluorescent Assays for Ceramide Synthase Activity.

Couttas TA, Don AS. Couttas TA, et al. Methods Mol Biol. 2016;1376:23-33. doi: 10.1007/978-1-4939-3170-5_3. Methods Mol Biol. 2016. PMID: 26552672

6

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease.

Couttas TA, Kain N, Suchowerska AK, Quek LE, Turner N, Fath T, Garner B, Don AS. Couttas TA, et al. Neurobiol Aging. 2016 Jul;43:89-100. doi: 10.1016/j.neurobiolaging.2016.03.027. Epub 2016 Apr 4. Neurobiol Aging. 2016. PMID: 27255818

7

Contextual fear conditioning is enhanced in mice lacking functional sphingosine kinase 2.

Lei M, Shafique A, Shang K, Couttas TA, Zhao H, Don AS, Karl T. Lei M, et al. Among authors: couttas ta. Behav Brain Res. 2017 Aug 30;333:9-16. doi: 10.1016/j.bbr.2017.06.019. Epub 2017 Jun 15. Behav Brain Res. 2017. PMID: 28625547

8

Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.

Chen J, Qi Y, Zhao Y, Kaczorowski D, Couttas TA, Coleman PR, Don AS, Bertolino P, Gamble JR, Vadas MA, Xia P, McCaughan GW. Chen J, et al. Among authors: couttas ta. Oncotarget. 2018 Feb 26;9(21):15635-15649. doi: 10.18632/oncotarget.24583. eCollection 2018 Mar 20. Oncotarget. 2018. PMID: 29643998 Free PMC article.

9

Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration.

Couttas TA, Kain N, Tran C, Chatterton Z, Kwok JB, Don AS. Couttas TA, et al. J Alzheimers Dis. 2018;63(2):503-514. doi: 10.3233/JAD-171054. J Alzheimers Dis. 2018. PMID: 29660940

10

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism.

Turner N, Lim XY, Toop HD, Osborne B, Brandon AE, Taylor EN, Fiveash CE, Govindaraju H, Teo JD, McEwen HP, Couttas TA, Butler SM, Das A, Kowalski GM, Bruce CR, Hoehn KL, Fath T, Schmitz-Peiffer C, Cooney GJ, Montgomery MK, Morris JC, Don AS. Turner N, et al. Among authors: couttas ta. Nat Commun. 2018 Aug 21;9(1):3165. doi: 10.1038/s41467-018-05613-7. Nat Commun. 2018. PMID: 30131496 Free PMC article.

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