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Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor-4.
Ohotski J, Rosen H, Bittman R, Pyne S, Pyne NJ. Ohotski J, et al. Cell Signal. 2014 May;26(5):1040-7. doi: 10.1016/j.cellsig.2014.01.023. Epub 2014 Jan 29. Cell Signal. 2014. PMID: 24486401 Free article.
The role of sphingosine 1-phosphate in inflammation and cancer.
Pyne NJ, Ohotski J, Bittman R, Pyne S. Pyne NJ, et al. Among authors: ohotski j. Adv Biol Regul. 2014 Jan;54:121-9. doi: 10.1016/j.jbior.2013.08.005. Epub 2013 Sep 11. Adv Biol Regul. 2014. PMID: 24070975 Free article. Review.
Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.
Rutherford C, Childs S, Ohotski J, McGlynn L, Riddick M, MacFarlane S, Tasker D, Pyne S, Pyne NJ, Edwards J, Palmer TM. Rutherford C, et al. Among authors: ohotski j. Cell Death Dis. 2013 Nov 21;4(11):e927. doi: 10.1038/cddis.2013.455. Cell Death Dis. 2013. PMID: 24263101 Free PMC article.