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USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.
Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, Zhang H, An L, Zhao Y, Xu X, Chen Z, Kogiso M, Zhang D, Zhang H, Zhang P, Jung JU, Li X, Xu G, Yang J. Fan Y, et al. Among authors: xu g, xu x. J Exp Med. 2014 Feb 10;211(2):313-28. doi: 10.1084/jem.20122844. Epub 2014 Feb 3. J Exp Med. 2014. PMID: 24493797 Free PMC article.
TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy.
Fan Y, Cheng J, Vasudevan SA, Patel RH, Liang L, Xu X, Zhao Y, Jia W, Lu F, Zhang H, Nuchtern JG, Kim ES, Yang J. Fan Y, et al. Among authors: xu x. Apoptosis. 2013 Oct;18(10):1224-34. doi: 10.1007/s10495-013-0864-0. Apoptosis. 2013. PMID: 23700229 Free PMC article.
The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model.
Lu J, Guan S, Zhao Y, Yu Y, Woodfield SE, Zhang H, Yang KL, Bieerkehazhi S, Qi L, Li X, Gu J, Xu X, Jin J, Muscal JA, Yang T, Xu GT, Yang J. Lu J, et al. Among authors: xu gt, xu x. Cancer Lett. 2017 Aug 1;400:61-68. doi: 10.1016/j.canlet.2017.04.022. Epub 2017 Apr 26. Cancer Lett. 2017. PMID: 28455243 Free PMC article.
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