O'Hayre M - Search Results

1

Novel insights into G protein and G protein-coupled receptor signaling in cancer.

O'Hayre M, Degese MS, Gutkind JS. O'Hayre M, et al. Curr Opin Cell Biol. 2014 Apr;27:126-35. doi: 10.1016/j.ceb.2014.01.005. Epub 2014 Feb 6. Curr Opin Cell Biol. 2014. PMID: 24508914 Free PMC article. Review.

2

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

O'Hayre M, Vázquez-Prado J, Kufareva I, Stawiski EW, Handel TM, Seshagiri S, Gutkind JS. O'Hayre M, et al. Nat Rev Cancer. 2013 Jun;13(6):412-24. doi: 10.1038/nrc3521. Epub 2013 May 3. Nat Rev Cancer. 2013. PMID: 23640210 Free PMC article. Review.

3

Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.

O'Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis CM, Drummond RA, Avino S, Finkel K, Kalim KW, DiPasquale G, Guo F, Aoki J, Zheng Y, Lionakis MS, Molinolo AA, Gutkind JS. O'Hayre M, et al. Oncogene. 2016 Jul 21;35(29):3771-80. doi: 10.1038/onc.2015.442. Epub 2015 Nov 30. Oncogene. 2016. PMID: 26616858 Free PMC article.

4

Genetic evidence that β-arrestins are dispensable for the initiation of β₂-adrenergic receptor signaling to ERK.

O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. O'Hayre M, et al. Sci Signal. 2017 Jun 20;10(484):eaal3395. doi: 10.1126/scisignal.aal3395. Sci Signal. 2017. PMID: 28634209 Free PMC article.

5

The homozygous CX3CR1-M280 mutation impairs human monocyte survival.

Collar AL, Swamydas M, O'Hayre M, Sajib MS, Hoffman KW, Singh SP, Mourad A, Johnson MD, Ferre EM, Farber JM, Lim JK, Mikelis CM, Gutkind JS, Lionakis MS. Collar AL, et al. Among authors: o hayre m. JCI Insight. 2018 Feb 8;3(3):e95417. doi: 10.1172/jci.insight.95417. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415879 Free PMC article.

6

Insights into β2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3.

Qi S, O'Hayre M, Gutkind JS, Hurley JH. Qi S, et al. Among authors: o hayre m. Protein Sci. 2014 Dec;23(12):1708-16. doi: 10.1002/pro.2549. Epub 2014 Sep 26. Protein Sci. 2014. PMID: 25220262 Free PMC article.

7

Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).

Qi S, O'Hayre M, Gutkind JS, Hurley JH. Qi S, et al. Among authors: o hayre m. J Biol Chem. 2014 Feb 21;289(8):4743-52. doi: 10.1074/jbc.M113.527473. Epub 2013 Dec 30. J Biol Chem. 2014. PMID: 24379409 Free PMC article.

8

Modulation of chemokine receptor activity through dimerization and crosstalk.

Salanga CL, O'Hayre M, Handel T. Salanga CL, et al. Cell Mol Life Sci. 2009 Apr;66(8):1370-86. doi: 10.1007/s00018-008-8666-1. Cell Mol Life Sci. 2009. PMID: 19099182 Free PMC article. Review.

9

Emerging concepts and approaches for chemokine-receptor drug discovery.

O'Hayre M, Salanga CL, Handel TM, Hamel DJ. O'Hayre M, et al. Expert Opin Drug Discov. 2010 Nov;5(11):1109-22. doi: 10.1517/17460441.2010.525633. Expert Opin Drug Discov. 2010. PMID: 21132095 Free PMC article. Review.

10

Phosphoproteomic analysis of chemokine signaling networks.

O'Hayre M, Salanga CL, Dorrestein PC, Handel TM. O'Hayre M, et al. Methods Enzymol. 2009;460:331-46. doi: 10.1016/S0076-6879(09)05216-1. Methods Enzymol. 2009. PMID: 19446733

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