Chiu WA - Search Results

1

Physiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse.

Chiu WA, Campbell JL Jr, Clewell HJ 3rd, Zhou YH, Wright FA, Guyton KZ, Rusyn I. Chiu WA, et al. Environ Health Perspect. 2014 May;122(5):456-63. doi: 10.1289/ehp.1307623. Epub 2014 Feb 11. Environ Health Perspect. 2014. PMID: 24518055 Free PMC article.

2

Comments on article "Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene" by Clewell and Andersen.

Caldwell JC, Evans MV, Marcus AH, Scott CS, Chiu WA, Okino MS, Preuss PW. Caldwell JC, et al. Among authors: chiu wa. Crit Rev Toxicol. 2006 Mar;36(3):291-4; discussion 295-8. doi: 10.1080/10408440600599240. Crit Rev Toxicol. 2006. PMID: 16686425

3

Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.

Hack CE, Chiu WA, Jay Zhao Q, Clewell HJ. Hack CE, et al. Among authors: chiu wa. Regul Toxicol Pharmacol. 2006 Oct;46(1):63-83. doi: 10.1016/j.yrtph.2006.05.012. Epub 2006 Aug 4. Regul Toxicol Pharmacol. 2006. PMID: 16889879

4

Key scientific issues in the health risk assessment of trichloroethylene.

Chiu WA, Caldwell JC, Keshava N, Scott CS. Chiu WA, et al. Environ Health Perspect. 2006 Sep;114(9):1445-9. doi: 10.1289/ehp.8690. Environ Health Perspect. 2006. PMID: 16966103 Free PMC article. Review.

5

Issues in the pharmacokinetics of trichloroethylene and its metabolites.

Chiu WA, Okino MS, Lipscomb JC, Evans MV. Chiu WA, et al. Environ Health Perspect. 2006 Sep;114(9):1450-6. doi: 10.1289/ehp.8691. Environ Health Perspect. 2006. PMID: 16966104 Free PMC article. Review.

6

Trichloroethylene cancer epidemiology: a consideration of select issues.

Scott CS, Chiu WA. Scott CS, et al. Among authors: chiu wa. Environ Health Perspect. 2006 Sep;114(9):1471-8. doi: 10.1289/ehp.8949. Environ Health Perspect. 2006. PMID: 16966107 Free PMC article. Review.

7

Toxicokinetics of inhaled trichloroethylene and tetrachloroethylene in humans at 1 ppm: empirical results and comparisons with previous studies.

Chiu WA, Micallef S, Monster AC, Bois FY. Chiu WA, et al. Toxicol Sci. 2007 Jan;95(1):23-36. doi: 10.1093/toxsci/kfl129. Epub 2006 Oct 10. Toxicol Sci. 2007. PMID: 17032701 Clinical Trial.

8

Evaluation of physiologically based pharmacokinetic models for use in risk assessment.

Chiu WA, Barton HA, DeWoskin RS, Schlosser P, Thompson CM, Sonawane B, Lipscomb JC, Krishnan K. Chiu WA, et al. J Appl Toxicol. 2007 May-Jun;27(3):218-37. doi: 10.1002/jat.1225. J Appl Toxicol. 2007. PMID: 17299829 Review.

9

Approaches for applications of physiologically based pharmacokinetic models in risk assessment.

Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Lipscomb JC, Schlosser P, Chiu WA, Krishnan K. Thompson CM, et al. Among authors: chiu wa. J Toxicol Environ Health B Crit Rev. 2008 Aug;11(7):519-47. doi: 10.1080/10937400701724337. J Toxicol Environ Health B Crit Rev. 2008. PMID: 18584453 Review.

10

Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly.

Evans MV, Chiu WA, Okino MS, Caldwell JC. Evans MV, et al. Among authors: chiu wa. Toxicol Appl Pharmacol. 2009 May 1;236(3):329-40. doi: 10.1016/j.taap.2009.02.013. Epub 2009 Feb 26. Toxicol Appl Pharmacol. 2009. PMID: 19249323

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