Tweedie DJ - Search Results

1

Enzyme kinetics in drug metabolism: fundamentals and applications.

Nagar S, Argikar UA, Tweedie DJ. Nagar S, et al. Among authors: tweedie dj. Methods Mol Biol. 2014;1113:1-6. doi: 10.1007/978-1-62703-758-7_1. Methods Mol Biol. 2014. PMID: 24523105

2

A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.

Korzekwa K, Tweedie D, Argikar UA, Whitcher-Johnstone A, Bell L, Bickford S, Nagar S. Korzekwa K, et al. Drug Metab Dispos. 2014 Sep;42(9):1587-95. doi: 10.1124/dmd.114.058297. Epub 2014 Jun 17. Drug Metab Dispos. 2014. PMID: 24939653 Free PMC article.

3

Case Study 4: Application of Basic Enzyme Kinetics to Metabolism Studies-Real-Life Examples.

Li Y, McCabe M, Podila L, Tracy TS, Tweedie D. Li Y, et al. Methods Mol Biol. 2021;2342:665-684. doi: 10.1007/978-1-0716-1554-6_23. Methods Mol Biol. 2021. PMID: 34272711

4

Case study 3. Application of basic enzyme kinetics to metabolism studies: real-life examples.

Li Y, McCabe M, Podila L, Tracy TS, Tweedie DJ. Li Y, et al. Among authors: tweedie dj. Methods Mol Biol. 2014;1113:441-60. doi: 10.1007/978-1-62703-758-7_20. Methods Mol Biol. 2014. PMID: 24523124

5

Case study 7. Compiled aha moments in enzyme kinetics: authors' experiences.

Tweedie DJ. Tweedie DJ. Methods Mol Biol. 2014;1113:513-9. doi: 10.1007/978-1-62703-758-7_24. Methods Mol Biol. 2014. PMID: 24523128

6

The role of transporters in toxicity and disease.

Schuetz JD, Swaan PW, Tweedie DJ. Schuetz JD, et al. Among authors: tweedie dj. Drug Metab Dispos. 2014 Apr;42(4):541-5. doi: 10.1124/dmd.114.057539. Drug Metab Dispos. 2014. PMID: 24598705 Free PMC article. Review.

7

Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4.

Hafey MJ, Aleksunes LM, Bridges CC, Brouwer KR, Chien HC, Leslie EM, Hu S, Li Y, Shen J, Sparreboom A, Sprowl J, Tweedie D, Lai Y. Hafey MJ, et al. Clin Pharmacol Ther. 2022 Sep;112(3):527-539. doi: 10.1002/cpt.2638. Epub 2022 Jun 10. Clin Pharmacol Ther. 2022. PMID: 35546260 Review.

8

Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients.

Sane RS, Steinmann GG, Huang Q, Li Y, Podila L, Mease K, Olson S, Taub ME, Stern JO, Nehmiz G, Böcher WO, Asselah T, Tweedie D. Sane RS, et al. J Pharmacol Exp Ther. 2014 Nov;351(2):403-12. doi: 10.1124/jpet.114.218081. Epub 2014 Sep 9. J Pharmacol Exp Ther. 2014. PMID: 25204339 Clinical Trial.

9

Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: in vitro and in vivo correlation.

Sabo JP, Kort J, Ballow C, Kashuba AD, Haschke M, Battegay M, Girlich B, Ting N, Lang B, Zhang W, Cooper C, O'Brien D, Seibert E, Chan TS, Tweedie D, Li Y. Sabo JP, et al. J Clin Pharmacol. 2015 Apr;55(4):467-77. doi: 10.1002/jcph.436. Epub 2015 Jan 14. J Clin Pharmacol. 2015. PMID: 25449227 Clinical Trial.

10

Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment.

Wong SG, Ramsden D, Dallas S, Fung C, Einolf HJ, Palamanda J, Chen L, Goosen TC, Siu YA, Zhang G, Tweedie D, Hariparsad N, Jones B, Yates PD. Wong SG, et al. Drug Metab Dispos. 2021 Jan;49(1):94-110. doi: 10.1124/dmd.120.000055. Epub 2020 Nov 2. Drug Metab Dispos. 2021. PMID: 33139460

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