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PICOT is a critical regulator of cardiac hypertrophy and cardiomyocyte contractility.
Cha H, Kim JM, Oh JG, Jeong MH, Park CS, Park J, Jeong HJ, Park BK, Lee YH, Jeong D, Yang DK, Bernecker OY, Kim DH, Hajjar RJ, Park WJ. Cha H, et al. Among authors: oh jg. J Mol Cell Cardiol. 2008 Dec;45(6):796-803. doi: 10.1016/j.yjmcc.2008.09.124. Epub 2008 Sep 27. J Mol Cell Cardiol. 2008. PMID: 18929570 Free PMC article.
SUMO1-dependent modulation of SERCA2a in heart failure.
Kho C, Lee A, Jeong D, Oh JG, Chaanine AH, Kizana E, Park WJ, Hajjar RJ. Kho C, et al. Among authors: oh jg. Nature. 2011 Sep 7;477(7366):601-5. doi: 10.1038/nature10407. Nature. 2011. PMID: 21900893 Free PMC article.
PICOT increases cardiac contractility by inhibiting PKCζ activity.
Oh JG, Jeong D, Cha H, Kim JM, Lifirsu E, Kim J, Yang DK, Park CS, Kho C, Park S, Yoo YJ, Kim DH, Kim J, Hajjar RJ, Park WJ. Oh JG, et al. J Mol Cell Cardiol. 2012 Jul;53(1):53-63. doi: 10.1016/j.yjmcc.2012.03.005. Epub 2012 Mar 17. J Mol Cell Cardiol. 2012. PMID: 22449794
Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress.
Park CS, Chen S, Lee H, Cha H, Oh JG, Hong S, Han P, Ginsburg KS, Jin S, Park I, Singh VP, Wang HS, Franzini-Armstrong C, Park WJ, Bers DM, Kranias EG, Cho C, Kim DH. Park CS, et al. Among authors: oh jg. Basic Res Cardiol. 2013 May;108(3):344. doi: 10.1007/s00395-013-0344-2. Epub 2013 Apr 4. Basic Res Cardiol. 2013. PMID: 23553082 Free PMC article.
84 results