Donigan KA - Search Results

1

The steric gate of DNA polymerase ι regulates ribonucleotide incorporation and deoxyribonucleotide fidelity.

Donigan KA, McLenigan MP, Yang W, Goodman MF, Woodgate R. Donigan KA, et al. J Biol Chem. 2014 Mar 28;289(13):9136-45. doi: 10.1074/jbc.M113.545442. Epub 2014 Feb 14. J Biol Chem. 2014. PMID: 24532793 Free PMC article.

2

Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae.

Donigan KA, Cerritelli SM, McDonald JP, Vaisman A, Crouch RJ, Woodgate R. Donigan KA, et al. DNA Repair (Amst). 2015 Nov;35:1-12. doi: 10.1016/j.dnarep.2015.07.002. Epub 2015 Aug 7. DNA Repair (Amst). 2015. PMID: 26340535 Free PMC article.

3

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.

Maul RW, MacCarthy T, Frank EG, Donigan KA, McLenigan MP, Yang W, Saribasak H, Huston DE, Lange SS, Woodgate R, Gearhart PJ. Maul RW, et al. Among authors: donigan ka. J Exp Med. 2016 Aug 22;213(9):1675-83. doi: 10.1084/jem.20151227. Epub 2016 Jul 25. J Exp Med. 2016. PMID: 27455952 Free PMC article.

4

Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.

Nemec AA, Donigan KA, Murphy DL, Jaeger J, Sweasy JB. Nemec AA, et al. Among authors: donigan ka. J Biol Chem. 2012 Jul 6;287(28):23840-9. doi: 10.1074/jbc.M112.362111. Epub 2012 May 9. J Biol Chem. 2012. PMID: 22573322 Free PMC article.

5

The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.

Nemec AA, Murphy DL, Donigan KA, Sweasy JB. Nemec AA, et al. Among authors: donigan ka. J Biol Chem. 2014 May 16;289(20):13708-16. doi: 10.1074/jbc.M114.550400. Epub 2014 Mar 25. J Biol Chem. 2014. PMID: 24668809 Free PMC article.

6

Human POLB gene is mutated in high percentage of colorectal tumors.

Donigan KA, Sun KW, Nemec AA, Murphy DL, Cong X, Northrup V, Zelterman D, Sweasy JB. Donigan KA, et al. J Biol Chem. 2012 Jul 6;287(28):23830-9. doi: 10.1074/jbc.M111.324947. Epub 2012 May 10. J Biol Chem. 2012. PMID: 22577134 Free PMC article.

7

The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation.

Donigan KA, Hile SE, Eckert KA, Sweasy JB. Donigan KA, et al. DNA Repair (Amst). 2012 Apr 1;11(4):381-90. doi: 10.1016/j.dnarep.2012.01.004. Epub 2012 Feb 15. DNA Repair (Amst). 2012. PMID: 22341651 Free PMC article.

8

DNA polymerase β variant Ile260Met generates global gene expression changes related to cellular transformation.

Donigan KA, Tuck D, Schulz V, Sweasy JB. Donigan KA, et al. Mutagenesis. 2012 Nov;27(6):683-91. doi: 10.1093/mutage/ges034. Epub 2012 Aug 21. Mutagenesis. 2012. PMID: 22914675 Free PMC article.

9

Sequence context-specific mutagenesis and base excision repair.

Donigan KA, Sweasy JB. Donigan KA, et al. Mol Carcinog. 2009 Apr;48(4):362-8. doi: 10.1002/mc.20497. Mol Carcinog. 2009. PMID: 19306280 Free PMC article. Review.

10

Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation.

Stachelek GC, Dalal S, Donigan KA, Campisi Hegan D, Sweasy JB, Glazer PM. Stachelek GC, et al. Among authors: donigan ka. Cancer Res. 2010 Jan 1;70(1):409-17. doi: 10.1158/0008-5472.CAN-09-1353. Epub 2009 Dec 22. Cancer Res. 2010. PMID: 20028873 Free PMC article.

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