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Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells.
Schmidt A, Meissner RS, Gentile MA, Chisamore MJ, Opas EE, Scafonas A, Cusick TE, Gambone C, Pennypacker B, Hodor P, Perkins JJ, Bai C, Ferraro D, Bettoun DJ, Wilkinson HA, Alves SE, Flores O, Ray WJ. Schmidt A, et al. Among authors: wilkinson ha. J Steroid Biochem Mol Biol. 2014 Sep;143:29-39. doi: 10.1016/j.jsbmb.2014.02.005. Epub 2014 Feb 22. J Steroid Biochem Mol Biol. 2014. PMID: 24565564
A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice.
Chisamore MJ, Gentile MA, Dillon GM, Baran M, Gambone C, Riley S, Schmidt A, Flores O, Wilkinson H, Alves SE. Chisamore MJ, et al. J Steroid Biochem Mol Biol. 2016 Oct;163:88-97. doi: 10.1016/j.jsbmb.2016.04.007. Epub 2016 Apr 19. J Steroid Biochem Mol Biol. 2016. PMID: 27106747
Non-invasive muscle contraction assay to study rodent models of sarcopenia.
Chiu CS, Weber H, Adamski S, Rauch A, Gentile MA, Alves SE, Kath G, Flores O, Wilkinson HA. Chiu CS, et al. Among authors: wilkinson ha. BMC Musculoskelet Disord. 2011 Oct 28;12:246. doi: 10.1186/1471-2474-12-246. BMC Musculoskelet Disord. 2011. PMID: 22035016 Free PMC article.
Direct agonist/antagonist functions of dehydroepiandrosterone.
Chen F, Knecht K, Birzin E, Fisher J, Wilkinson H, Mojena M, Moreno CT, Schmidt A, Harada S, Freedman LP, Reszka AA. Chen F, et al. Endocrinology. 2005 Nov;146(11):4568-76. doi: 10.1210/en.2005-0368. Epub 2005 Jun 30. Endocrinology. 2005. PMID: 15994348
140 results