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543 results

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Page 1
NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.
Eisfeld AK, Schwind S, Hoag KW, Walker CJ, Liyanarachchi S, Patel R, Huang X, Markowitz J, Duan W, Otterson GA, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A. Eisfeld AK, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4179-84. doi: 10.1073/pnas.1401727111. Epub 2014 Feb 28. Proc Natl Acad Sci U S A. 2014. PMID: 24586049 Free PMC article.
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia.
Eisfeld AK, Marcucci G, Liyanarachchi S, Döhner K, Schwind S, Maharry K, Leffel B, Döhner H, Radmacher MD, Bloomfield CD, Tanner SM, de la Chapelle A. Eisfeld AK, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6668-73. doi: 10.1073/pnas.1203756109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493267 Free PMC article.
Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes.
Baldus CD, Liyanarachchi S, Mrózek K, Auer H, Tanner SM, Guimond M, Ruppert AS, Mohamed N, Davuluri RV, Caligiuri MA, Bloomfield CD, de la Chapelle A. Baldus CD, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3915-20. doi: 10.1073/pnas.0400272101. Epub 2004 Mar 8. Proc Natl Acad Sci U S A. 2004. PMID: 15007164 Free PMC article.
MicroRNA fingerprints during human megakaryocytopoiesis.
Garzon R, Pichiorri F, Palumbo T, Iuliano R, Cimmino A, Aqeilan R, Volinia S, Bhatt D, Alder H, Marcucci G, Calin GA, Liu CG, Bloomfield CD, Andreeff M, Croce CM. Garzon R, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5078-83. doi: 10.1073/pnas.0600587103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549775 Free PMC article.
Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway.
Eisfeld AK, Schwind S, Patel R, Huang X, Santhanam R, Walker CJ, Markowitz J, Hoag KW, Jarvinen TM, Leffel B, Perrotti D, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A. Eisfeld AK, et al. Among authors: bloomfield cd. Sci Signal. 2014 Apr 15;7(321):ra36. doi: 10.1126/scisignal.2004762. Sci Signal. 2014. PMID: 24736457 Free PMC article.
Expression and prognostic impact of lncRNAs in acute myeloid leukemia.
Garzon R, Volinia S, Papaioannou D, Nicolet D, Kohlschmidt J, Yan PS, Mrózek K, Bucci D, Carroll AJ, Baer MR, Wetzler M, Carter TH, Powell BL, Kolitz JE, Moore JO, Eisfeld AK, Blachly JS, Blum W, Caligiuri MA, Stone RM, Marcucci G, Croce CM, Byrd JC, Bloomfield CD. Garzon R, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18679-84. doi: 10.1073/pnas.1422050112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512507 Free PMC article. Clinical Trial.
Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia.
Maharry SE, Walker CJ, Liyanarachchi S, Mehta S, Patel M, Bainazar MA, Huang X, Lankenau MA, Hoag KW, Ranganathan P, Garzon R, Blachly JS, Guttridge DC, Bloomfield CD, de la Chapelle A, Eisfeld AK. Maharry SE, et al. Among authors: bloomfield cd. Cancer Discov. 2016 Sep;6(9):1036-51. doi: 10.1158/2159-8290.CD-16-0023. Epub 2016 Jun 27. Cancer Discov. 2016. PMID: 27354268 Free PMC article.
Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia.
Huang X, Schwind S, Santhanam R, Eisfeld AK, Chiang CL, Lankenau M, Yu B, Hoellerbauer P, Jin Y, Tarighat SS, Khalife J, Walker A, Perrotti D, Bloomfield CD, Wang H, Lee RJ, Lee LJ, Marcucci G. Huang X, et al. Among authors: bloomfield cd. Oncotarget. 2016 Sep 13;7(37):59273-59286. doi: 10.18632/oncotarget.11150. Oncotarget. 2016. PMID: 27517749 Free PMC article.
Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD. Bill M, et al. Among authors: bloomfield cd. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26340-26346. doi: 10.1073/pnas.2014732117. Epub 2020 Oct 5. Proc Natl Acad Sci U S A. 2020. PMID: 33020282 Free PMC article.
543 results