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Page 1
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. Gilbert PM, et al. Among authors: lakins jn. J Clin Invest. 2010 May;120(5):1535-50. doi: 10.1172/JCI39534. Epub 2010 Apr 12. J Clin Invest. 2010. PMID: 20389018 Free PMC article.
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Laklai H, et al. Among authors: lakins jn. Nat Med. 2016 May;22(5):497-505. doi: 10.1038/nm.4082. Epub 2016 Apr 18. Nat Med. 2016. PMID: 27089513 Free PMC article.
Matrix crosslinking forces tumor progression by enhancing integrin signaling.
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Levental KR, et al. Among authors: lakins jn. Cell. 2009 Nov 25;139(5):891-906. doi: 10.1016/j.cell.2009.10.027. Cell. 2009. PMID: 19931152 Free PMC article.
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. Maller O, et al. Among authors: lakins jn. Nat Mater. 2021 Apr;20(4):548-559. doi: 10.1038/s41563-020-00849-5. Epub 2020 Nov 30. Nat Mater. 2021. PMID: 33257795 Free PMC article.
47 results