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Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies.
Bousquet J, Jorgensen C, Dauzat M, Cesario A, Camuzat T, Bourret R, Best N, Anto JM, Abecassis F, Aubas P, Avignon A, Badin M, Bedbrook A, Blain H, Bourdin A, Bringer J, Camu W, Cayla G, Costa DJ, Courtet P, Cristol JP, Demoly P, de la Coussaye JE, Fesler P, Gouzi F, Gris JC, Guillot B, Hayot M, Jeandel C, Jonquet O, Journot L, Lehmann S, Mathieu G, Morel J, Ninot G, Pelissier J, Picot MC, Radier-Pontal F, Robine JM, Rodier M, Roubille F, Sultan A, Wojtusciszyn A, Auffray C, Balling R, Barbara C, Cambon-Thomsen A, Chavannes NH, Chuchalin A, Crooks G, Dedeu A, Fabbri LM, Garcia-Aymerich J, Hajjam J, Melo Gomes E, Palkonen S, Piette F, Pison C, Price D, Samolinski B, Schunemann HJ, Sterk PJ, Yiallouros P, Roca J, Van de Perre P, Mercier J. Bousquet J, et al. Among authors: mercier j. Curr Pharm Des. 2014;20(38):5928-44. doi: 10.2174/1381612820666140314115505. Curr Pharm Des. 2014. PMID: 24641234 Review.
Systems medicine and integrated care to combat chronic noncommunicable diseases.
Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Bousquet J, et al. Among authors: mercier j. Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259. Genome Med. 2011. PMID: 21745417 Free PMC article.
Grape polyphenols prevent fructose-induced oxidative stress and insulin resistance in first-degree relatives of type 2 diabetic patients.
Hokayem M, Blond E, Vidal H, Lambert K, Meugnier E, Feillet-Coudray C, Coudray C, Pesenti S, Luyton C, Lambert-Porcheron S, Sauvinet V, Fedou C, Brun JF, Rieusset J, Bisbal C, Sultan A, Mercier J, Goudable J, Dupuy AM, Cristol JP, Laville M, Avignon A. Hokayem M, et al. Among authors: mercier j. Diabetes Care. 2013 Jun;36(6):1454-61. doi: 10.2337/dc12-1652. Epub 2012 Dec 28. Diabetes Care. 2013. PMID: 23275372 Free PMC article. Clinical Trial.
Fiber atrophy, oxidative stress, and oxidative fiber reduction are the attributes of different phenotypes in chronic obstructive pulmonary disease patients.
Gouzi F, Abdellaoui A, Molinari N, Pinot E, Ayoub B, Laoudj-Chenivesse D, Cristol JP, Mercier J, Hayot M, Préfaut C. Gouzi F, et al. Among authors: mercier j. J Appl Physiol (1985). 2013 Dec;115(12):1796-805. doi: 10.1152/japplphysiol.00778.2013. Epub 2013 Oct 17. J Appl Physiol (1985). 2013. PMID: 24136107 Free article.
Reference values for vastus lateralis fiber type proportion and fiber size.
Gouzi F, Maury J, Molinari N, Pomiès P, Mercier J, Préfaut C, Hayot M. Gouzi F, et al. Among authors: mercier j. J Appl Physiol (1985). 2014 Jan 15;116(2):228. doi: 10.1152/japplphysiol.01332.2013. J Appl Physiol (1985). 2014. PMID: 24429104 Free article. No abstract available.
Effects of vitamin C, vitamin E, zinc gluconate, and selenomethionine supplementation on muscle function and oxidative stress biomarkers in patients with facioscapulohumeral dystrophy: a double-blind randomized controlled clinical trial.
Passerieux E, Hayot M, Jaussent A, Carnac G, Gouzi F, Pillard F, Picot MC, Böcker K, Hugon G, Pincemail J, Defraigne JO, Verrips T, Mercier J, Laoudj-Chenivesse D. Passerieux E, et al. Among authors: mercier j. Free Radic Biol Med. 2015 Apr;81:158-69. doi: 10.1016/j.freeradbiomed.2014.09.014. Epub 2014 Sep 20. Free Radic Biol Med. 2015. PMID: 25246239 Clinical Trial.
1,126 results