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12 results

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Page 1
Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.
Owen DR, Guo Q, Kalk NJ, Colasanti A, Kalogiannopoulou D, Dimber R, Lewis YL, Libri V, Barletta J, Ramada-Magalhaes J, Kamalakaran A, Nutt DJ, Passchier J, Matthews PM, Gunn RN, Rabiner EA. Owen DR, et al. Among authors: lewis yl. J Cereb Blood Flow Metab. 2014 Jun;34(6):989-94. doi: 10.1038/jcbfm.2014.46. Epub 2014 Mar 19. J Cereb Blood Flow Metab. 2014. PMID: 24643083 Free PMC article. Clinical Trial.
Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge.
Erritzoe D, Ashok AH, Searle GE, Colasanti A, Turton S, Lewis Y, Huiban M, Moz S, Passchier J, Saleem A, Beaver J, Lingford-Hughes A, Nutt DJ, Howes OD, Gunn RN, Knudsen GM, Rabiner EA. Erritzoe D, et al. Neuropsychopharmacology. 2020 Apr;45(5):804-810. doi: 10.1038/s41386-019-0567-5. Epub 2019 Nov 12. Neuropsychopharmacology. 2020. PMID: 31715617 Free PMC article.
Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [11C]PHNO PET.
Rabiner EA, Uz T, Mansur A, Brown T, Chen G, Wu J, Atienza J, Schwarz AJ, Yin W, Lewis Y, Searle GE, Dennison JMTJ, Passchier J, Gunn RN, Tauscher J. Rabiner EA, et al. Neuropsychopharmacology. 2022 Jun;47(7):1405-1412. doi: 10.1038/s41386-021-01204-1. Epub 2021 Oct 21. Neuropsychopharmacology. 2022. PMID: 34675381 Free PMC article.
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Venkataraman AV, Mansur A, Rizzo G, Bishop C, Lewis Y, Kocagoncu E, Lingford-Hughes A, Huiban M, Passchier J, Rowe JB, Tsukada H, Brooks DJ, Martarello L, Comley RA, Chen L, Schwarz AJ, Hargreaves R, Gunn RN, Rabiner EA, Matthews PM. Venkataraman AV, et al. Sci Transl Med. 2022 Aug 17;14(658):eabk1051. doi: 10.1126/scitranslmed.abk1051. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976998
Brain Serotonin Release Is Reduced in Patients With Depression: A [11C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge.
Erritzoe D, Godlewska BR, Rizzo G, Searle GE, Agnorelli C, Lewis Y, Ashok AH, Colasanti A, Boura I, Farrell C, Parfitt H, Howes O, Passchier J, Gunn RN, Politis M, Nutt DJ, Cowen PJ, Knudsen GM, Rabiner EA. Erritzoe D, et al. Biol Psychiatry. 2023 Jun 15;93(12):1089-1098. doi: 10.1016/j.biopsych.2022.10.012. Epub 2022 Oct 29. Biol Psychiatry. 2023. PMID: 36635177
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [11C]GSK2256098.
Brown NF, Williams M, Arkenau HT, Fleming RA, Tolson J, Yan L, Zhang J, Singh R, Auger KR, Lenox L, Cox D, Lewis Y, Plisson C, Searle G, Saleem A, Blagden S, Mulholland P. Brown NF, et al. Neuro Oncol. 2018 Nov 12;20(12):1634-1642. doi: 10.1093/neuonc/noy078. Neuro Oncol. 2018. PMID: 29788497 Free PMC article. Clinical Trial.
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