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Page 1
Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice.
Willecke F, Tiwari S, Rupprecht B, Wolf D, Hergeth S, Hoppe N, Dufner B, Schulte L, Anto Michel N, Bukosza N, Marchini T, Jäckel M, Stachon P, Hilgendorf I, Zeschky K, Schleicher R, Langer HF, von Zur Muhlen C, Bode C, Peter K, Zirlik A. Willecke F, et al. Among authors: zeschky k. Thromb Haemost. 2014 Aug;112(2):379-89. doi: 10.1160/TH13-08-0653. Epub 2014 Mar 20. Thromb Haemost. 2014. PMID: 24652469
Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
Wolf D, Hohmann JD, Wiedemann A, Bledzka K, Blankenbach H, Marchini T, Gutte K, Zeschky K, Bassler N, Hoppe N, Rodriguez AO, Herr N, Hilgendorf I, Stachon P, Willecke F, Duerschmied D, von zur Muhlen C, Soloviev DA, Zhang L, Bode C, Plow EF, Libby P, Peter K, Zirlik A. Wolf D, et al. Among authors: zeschky k. Circ Res. 2011 Nov 11;109(11):1269-79. doi: 10.1161/CIRCRESAHA.111.247684. Epub 2011 Oct 13. Circ Res. 2011. PMID: 21998326 Free PMC article.
Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice.
Willecke F, Zeschky K, Ortiz Rodriguez A, Colberg C, Auwärter V, Kneisel S, Hutter M, Lozhkin A, Hoppe N, Wolf D, von zur Mühlen C, Moser M, Hilgendorf I, Bode C, Zirlik A. Willecke F, et al. Among authors: zeschky k. PLoS One. 2011 Apr 26;6(4):e19405. doi: 10.1371/journal.pone.0019405. PLoS One. 2011. PMID: 21541300 Free PMC article.
The oral spleen tyrosine kinase inhibitor fostamatinib attenuates inflammation and atherogenesis in low-density lipoprotein receptor-deficient mice.
Hilgendorf I, Eisele S, Remer I, Schmitz J, Zeschky K, Colberg C, Stachon P, Wolf D, Willecke F, Buchner M, Zirlik K, Ortiz-Rodriguez A, Lozhkin A, Hoppe N, von zur Muhlen C, zur Hausen A, Bode C, Zirlik A. Hilgendorf I, et al. Among authors: zeschky k. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):1991-9. doi: 10.1161/ATVBAHA.111.230847. Epub 2011 Jun 23. Arterioscler Thromb Vasc Biol. 2011. PMID: 21700926