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Page 1
Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates.
Barrett SE, Burke RS, Abrams MT, Bason C, Busuek M, Carlini E, Carr BA, Crocker LS, Fan H, Garbaccio RM, Guidry EN, Heo JH, Howell BJ, Kemp EA, Kowtoniuk RA, Latham AH, Leone AM, Lyman M, Parmar RG, Patel M, Pechenov SY, Pei T, Pudvah NT, Raab C, Riley S, Sepp-Lorenzino L, Smith S, Soli ED, Staskiewicz S, Stern M, Truong Q, Vavrek M, Waldman JH, Walsh ES, Williams JM, Young S, Colletti SL. Barrett SE, et al. Among authors: pechenov sy. J Control Release. 2014 Jun 10;183:124-37. doi: 10.1016/j.jconrel.2014.03.028. Epub 2014 Mar 21. J Control Release. 2014. PMID: 24657948
An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.
Barrett SE, Abrams MT, Burke R, Carr BA, Crocker LS, Garbaccio RM, Howell BJ, Kemp EA, Kowtoniuk RA, Latham AH, Leander KR, Leone AM, Patel M, Pechenov S, Pudvah NT, Riley S, Sepp-Lorenzino L, Walsh ES, Williams JM, Colletti SL. Barrett SE, et al. Int J Pharm. 2014 May 15;466(1-2):58-67. doi: 10.1016/j.ijpharm.2014.03.011. Epub 2014 Mar 5. Int J Pharm. 2014. PMID: 24607208
Crystalline monoclonal antibodies for subcutaneous delivery.
Yang MX, Shenoy B, Disttler M, Patel R, McGrath M, Pechenov S, Margolin AL. Yang MX, et al. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6934-9. doi: 10.1073/pnas.1131899100. Epub 2003 Jun 2. Proc Natl Acad Sci U S A. 2003. PMID: 12782786 Free PMC article.
Novel long-acting crystal formulation of human growth hormone.
Govardhan C, Khalaf N, Jung CW, Simeone B, Higbie A, Qu S, Chemmalil L, Pechenov S, Basu SK, Margolin AL. Govardhan C, et al. Pharm Res. 2005 Sep;22(9):1461-70. doi: 10.1007/s11095-005-6021-x. Epub 2005 Aug 24. Pharm Res. 2005. PMID: 16132358
Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation.
Tyagi P, Patel C, Gibson K, MacDougall F, Pechenov SY, Will S, Revell J, Huang Y, Rosenbaum AI, Balic K, Maharoof U, Grimsby J, Subramony JA. Tyagi P, et al. Among authors: pechenov sy. Pharmaceutics. 2023 Oct 9;15(10):2436. doi: 10.3390/pharmaceutics15102436. Pharmaceutics. 2023. PMID: 37896196 Free PMC article.