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Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.
Phillips DP, Gao W, Yang Y, Zhang G, Lerario IK, Lau TL, Jiang J, Wang X, Nguyen DG, Bhat BG, Trotter C, Sullivan H, Welzel G, Landry J, Chen Y, Joseph SB, Li C, Gordon WP, Richmond W, Johnson K, Bretz A, Bursulaya B, Pan S, McNamara P, Seidel HM. Phillips DP, et al. J Med Chem. 2014 Apr 24;57(8):3263-82. doi: 10.1021/jm401731q. Epub 2014 Apr 4. J Med Chem. 2014. PMID: 24666203
5(Z)-benzylidene-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5H-1-aza-6-oxa-chrysenes as non-steroidal glucocorticoid receptor modulators.
Ardecky RJ, Hudson AR, Phillips DP, Tyhonas JS, Deckhut C, Lau TL, Li Y, Martinborough EA, Roach SL, Higuchi RI, Lopez FJ, Marschke KB, Miner JN, Karanewsky DS, Negro-Vilar A, Zhi L. Ardecky RJ, et al. Among authors: phillips dp. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4158-62. doi: 10.1016/j.bmcl.2007.05.062. Epub 2007 May 23. Bioorg Med Chem Lett. 2007. PMID: 17553679
Synthesis and characterization of nonsteroidal glucocorticoid receptor modulators for multiple myeloma.
Hudson AR, Roach SL, Higuchi RI, Phillips DP, Bissonnette RP, Lamph WW, Yen J, Li Y, Adams ME, Valdez LJ, Vassar A, Cuervo C, Kallel EA, Gharbaoui CJ, Mais DE, Miner JN, Marschke KB, Rungta D, Negro-Vilar A, Zhi L. Hudson AR, et al. Among authors: phillips dp. J Med Chem. 2007 Sep 20;50(19):4699-709. doi: 10.1021/jm070370z. Epub 2007 Aug 17. J Med Chem. 2007. PMID: 17705362
Total synthesis of dysiherbaine.
Phillips D, Chamberlin AR. Phillips D, et al. J Org Chem. 2002 May 17;67(10):3194-201. doi: 10.1021/jo0107610. J Org Chem. 2002. PMID: 12003525
Amiodarone induced movement disorder after cardiac arrest - A case report.
Ratay CR, Doshi AA, Steinberg A, Kaczorowski D, Phillips DP, Rhinehart ZJ, Fozard J, Rivosecchi RM, Schatz KW, Bahl KD, Schwarm P, Coppler PJ. Ratay CR, et al. Among authors: phillips dp. Resusc Plus. 2022 Jul 6;11:100272. doi: 10.1016/j.resplu.2022.100272. eCollection 2022 Sep. Resusc Plus. 2022. PMID: 35832320 Free PMC article.
Patient Work and Their Contexts: Scoping Review.
Yin K, Jung J, Coiera E, Laranjo L, Blandford A, Khoja A, Tai WT, Phillips DP, Lau AYS. Yin K, et al. Among authors: phillips dp. J Med Internet Res. 2020 Jun 2;22(6):e16656. doi: 10.2196/16656. J Med Internet Res. 2020. PMID: 32484449 Free PMC article. Review.
157 results