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Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line.
Rebelo SL, Amel-Kashipaz MR, Radford PM, Bainbridge SE, Fiets R, Fang J, McDermott EM, Powell RJ, Todd I, Tighe PJ. Rebelo SL, et al. Among authors: powell rj. Arthritis Rheum. 2009 Jan;60(1):269-80. doi: 10.1002/art.24147. Arthritis Rheum. 2009. PMID: 19116900 Free article.
A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing.
Todd I, Negm OH, Reps J, Radford P, Figueredo G, McDermott EM, Drewe E, Powell RJ, Bainbridge S, Hamed M, Crouch S, Garibaldi J, St-Gallay S, Fairclough LC, Tighe PJ. Todd I, et al. Among authors: powell rj. Pharmacol Res. 2017 Nov;125(Pt B):188-200. doi: 10.1016/j.phrs.2017.08.012. Epub 2017 Aug 30. Pharmacol Res. 2017. PMID: 28860008
Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour.
Todd I, Radford PM, Draper-Morgan KA, McIntosh R, Bainbridge S, Dickinson P, Jamhawi L, Sansaridis M, Huggins ML, Tighe PJ, Powell RJ. Todd I, et al. Among authors: powell rj. Immunology. 2004 Sep;113(1):65-79. doi: 10.1111/j.1365-2567.2004.01942.x. Immunology. 2004. PMID: 15312137 Free PMC article.
372 results