O'Malley TT - Search Results

1

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Hong S, et al. Neuron. 2014 Apr 16;82(2):308-19. doi: 10.1016/j.neuron.2014.02.027. Epub 2014 Mar 27. Neuron. 2014. PMID: 24685176 Free PMC article.

2

New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF.

Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. Yang T, et al. Alzheimers Dement. 2013 Mar;9(2):99-112. doi: 10.1016/j.jalz.2012.11.005. Epub 2013 Jan 30. Alzheimers Dement. 2013. PMID: 23375565 Free PMC article.

3

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.

Hu NW, Nicoll AJ, Zhang D, Mably AJ, O'Malley T, Purro SA, Terry C, Collinge J, Walsh DM, Rowan MJ. Hu NW, et al. Nat Commun. 2014 Mar 4;5:3374. doi: 10.1038/ncomms4374. Nat Commun. 2014. PMID: 24594908 Free PMC article.

4

A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid.

Yang T, O'Malley TT, Kanmert D, Jerecic J, Zieske LR, Zetterberg H, Hyman BT, Walsh DM, Selkoe DJ. Yang T, et al. Alzheimers Res Ther. 2015 Mar 22;7(1):14. doi: 10.1186/s13195-015-0100-y. eCollection 2015. Alzheimers Res Ther. 2015. PMID: 25802556 Free PMC article.

5

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death.

Kanmert D, Cantlon A, Muratore CR, Jin M, O'Malley TT, Lee G, Young-Pearse TL, Selkoe DJ, Walsh DM. Kanmert D, et al. J Neurosci. 2015 Jul 29;35(30):10851-65. doi: 10.1523/JNEUROSCI.0387-15.2015. J Neurosci. 2015. PMID: 26224867 Free PMC article.

6

Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance.

Lei M, Xu H, Li Z, Wang Z, O'Malley TT, Zhang D, Walsh DM, Xu P, Selkoe DJ, Li S. Lei M, et al. Among authors: o malley tt. Neurobiol Dis. 2016 Jan;85:111-121. doi: 10.1016/j.nbd.2015.10.019. Epub 2015 Oct 22. Neurobiol Dis. 2016. PMID: 26525100 Free PMC article.

7

Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer's disease brain.

Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DM. Hong W, et al. Among authors: o malley tt. Acta Neuropathol. 2018 Jul;136(1):19-40. doi: 10.1007/s00401-018-1846-7. Epub 2018 Apr 23. Acta Neuropathol. 2018. PMID: 29687257 Free PMC article.

8

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer's disease.

Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DM. Jin M, et al. Among authors: o malley tt. Nat Commun. 2018 Jul 11;9(1):2676. doi: 10.1038/s41467-018-05068-w. Nat Commun. 2018. PMID: 29992960 Free PMC article.

9

Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain.

Brinkmalm G, Hong W, Wang Z, Liu W, O'Malley TT, Sun X, Frosch MP, Selkoe DJ, Portelius E, Zetterberg H, Blennow K, Walsh DM. Brinkmalm G, et al. Among authors: o malley tt. Brain. 2019 May 1;142(5):1441-1457. doi: 10.1093/brain/awz066. Brain. 2019. PMID: 31032851 Free PMC article.

10

Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies.

O'Malley TT, Oktaviani NA, Zhang D, Lomakin A, O'Nuallain B, Linse S, Benedek GB, Rowan MJ, Mulder FA, Walsh DM. O'Malley TT, et al. Biochem J. 2014 Aug 1;461(3):413-26. doi: 10.1042/BJ20140219. Biochem J. 2014. PMID: 24785004

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

25 results

Search Page

Filters