Aiba Y - Search Results

1

Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.

Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR. Hu J, et al. Among authors: aiba y. Nucleic Acid Ther. 2014 Jun;24(3):199-209. doi: 10.1089/nat.2013.0476. Epub 2014 Apr 2. Nucleic Acid Ther. 2014. PMID: 24694346 Free PMC article.

2

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.

Liu J, Yu D, Aiba Y, Pendergraff H, Swayze EE, Lima WF, Hu J, Prakash TP, Corey DR. Liu J, et al. Among authors: aiba y. Nucleic Acids Res. 2013 Nov;41(20):9570-83. doi: 10.1093/nar/gkt693. Epub 2013 Aug 9. Nucleic Acids Res. 2013. PMID: 23935115 Free PMC article.

3

Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions.

Aiba Y, Hu J, Liu J, Xiang Q, Martinez C, Corey DR. Aiba Y, et al. Biochemistry. 2013 Dec 23;52(51):9329-38. doi: 10.1021/bi4014209. Epub 2013 Nov 27. Biochemistry. 2013. PMID: 24266403 Free PMC article.

4

Promotion of double-duplex invasion of peptide nucleic acids through conjugation with nuclear localization signal peptide.

Aiba Y, Honda Y, Komiyama M. Aiba Y, et al. Chemistry. 2015 Mar 2;21(10):4021-6. doi: 10.1002/chem.201406085. Epub 2015 Jan 29. Chemistry. 2015. PMID: 25640012

5

Highly active artificial restriction enzyme composed of Ce(IV)/EDTA and PNA bearing phosphate group--relationship between the promotion by phosphate and the structure of invasion complex.

Aiba Y, Yamamoto Y, Komiyama M. Aiba Y, et al. Nucleic Acids Symp Ser (Oxf). 2006;(50):255-6. doi: 10.1093/nass/nrl127. Nucleic Acids Symp Ser (Oxf). 2006. PMID: 17150914

6

Solid-phase synthesis of pseudo-complementary peptide nucleic acids.

Komiyama M, Aiba Y, Ishizuka T, Sumaoka J. Komiyama M, et al. Among authors: aiba y. Nat Protoc. 2008;3(4):646-54. doi: 10.1038/nprot.2008.6. Nat Protoc. 2008. PMID: 18388947

7

Introduction of linkers into PNA for versatile applications.

Aiba Y, Komiyama M. Aiba Y, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):143-4. doi: 10.1093/nass/nrn073. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776294

8

Handy and prompt DNA separation using PNA with internal disulfide bond.

Aiba Y, Komiyama M. Aiba Y, et al. Nucleic Acids Symp Ser (Oxf). 2009;(53):175-6. doi: 10.1093/nass/nrp088. Nucleic Acids Symp Ser (Oxf). 2009. PMID: 19749317

9

Oxidation of an oligonucleotide-bound Ce(III)/multiphosphonate complex for site-selective DNA scission.

Lönnberg T, Aiba Y, Hamano Y, Miyajima Y, Sumaoka J, Komiyama M. Lönnberg T, et al. Among authors: aiba y. Chemistry. 2010 Jan 18;16(3):855-9. doi: 10.1002/chem.200902169. Chemistry. 2010. PMID: 19938010

10

Introduction of disulfide bond to the main chain of PNA to switch its hybridization and invasion activity.

Aiba Y, Komiyama M. Aiba Y, et al. Org Biomol Chem. 2009 Dec 21;7(24):5078-83. doi: 10.1039/b917405b. Epub 2009 Oct 20. Org Biomol Chem. 2009. PMID: 20024101

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