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Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs.
Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR. Hu J, et al. Among authors: swayze ee. Nucleic Acid Ther. 2014 Jun;24(3):199-209. doi: 10.1089/nat.2013.0476. Epub 2014 Apr 2. Nucleic Acid Ther. 2014. PMID: 24694346 Free PMC article.
Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.
Gagnon KT, Pendergraff HM, Deleavey GF, Swayze EE, Potier P, Randolph J, Roesch EB, Chattopadhyaya J, Damha MJ, Bennett CF, Montaillier C, Lemaitre M, Corey DR. Gagnon KT, et al. Among authors: swayze ee. Biochemistry. 2010 Nov 30;49(47):10166-78. doi: 10.1021/bi101208k. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21028906 Free PMC article.
Single-stranded siRNAs activate RNAi in animals.
Lima WF, Prakash TP, Murray HM, Kinberger GA, Li W, Chappell AE, Li CS, Murray SF, Gaus H, Seth PP, Swayze EE, Crooke ST. Lima WF, et al. Among authors: swayze ee. Cell. 2012 Aug 31;150(5):883-94. doi: 10.1016/j.cell.2012.08.014. Cell. 2012. PMID: 22939618 Free article.
149 results