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1,872 results

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Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
Chen EY, DeRan MT, Ignatius MS, Grandinetti KB, Clagg R, McCarthy KM, Lobbardi RM, Brockmann J, Keller C, Wu X, Langenau DM. Chen EY, et al. Among authors: keller c. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5349-54. doi: 10.1073/pnas.1317731111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706870 Free PMC article.
Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma.
Chen EY, Dobrinski KP, Brown KH, Clagg R, Edelman E, Ignatius MS, Chen JY, Brockmann J, Nielsen GP, Ramaswamy S, Keller C, Lee C, Langenau DM. Chen EY, et al. Among authors: keller c. PLoS Genet. 2013 Aug;9(8):e1003727. doi: 10.1371/journal.pgen.1003727. Epub 2013 Aug 29. PLoS Genet. 2013. PMID: 24009521 Free PMC article.
PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma.
Aslam MI, Abraham J, Mansoor A, Druker BJ, Tyner JW, Keller C. Aslam MI, et al. Among authors: keller c. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6383-8. doi: 10.1073/pnas.1403608111. Epub 2014 Apr 14. Proc Natl Acad Sci U S A. 2014. PMID: 24733895 Free PMC article.
Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. Abraham J, et al. Among authors: keller c. Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114. Genes Dev. 2014. PMID: 25030697 Free PMC article.
Rhabdomyosarcoma: current challenges and their implications for developing therapies.
Hettmer S, Li Z, Billin AN, Barr FG, Cornelison DD, Ehrlich AR, Guttridge DC, Hayes-Jordan A, Helman LJ, Houghton PJ, Khan J, Langenau DM, Linardic CM, Pal R, Partridge TA, Pavlath GK, Rota R, Schäfer BW, Shipley J, Stillman B, Wexler LH, Wagers AJ, Keller C. Hettmer S, et al. Among authors: keller c. Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a025650. doi: 10.1101/cshperspect.a025650. Cold Spring Harb Perspect Med. 2014. PMID: 25368019 Free PMC article. Review.
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
Ignatius MS, Hayes MN, Lobbardi R, Chen EY, McCarthy KM, Sreenivas P, Motala Z, Durbin AD, Molodtsov A, Reeder S, Jin A, Sindiri S, Beleyea BC, Bhere D, Alexander MS, Shah K, Keller C, Linardic CM, Nielsen PG, Malkin D, Khan J, Langenau DM. Ignatius MS, et al. Among authors: keller c. Cell Rep. 2017 Jun 13;19(11):2304-2318. doi: 10.1016/j.celrep.2017.05.061. Cell Rep. 2017. PMID: 28614716 Free PMC article.
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma.
Bharathy N, Svalina MN, Settelmeyer TP, Cleary MM, Berlow NE, Airhart SD, Xiang S, Keck J, Hayden JB, Shern JF, Mansoor A, Lathara M, Srinivasa G, Langenau DM, Keller C. Bharathy N, et al. Among authors: keller c. Oncotarget. 2017 Jun 16;8(38):62976-62983. doi: 10.18632/oncotarget.18520. eCollection 2017 Sep 8. Oncotarget. 2017. PMID: 28968964 Free PMC article.
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.
Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Pal R, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C. Bharathy N, et al. Among authors: keller c. Skelet Muscle. 2019 May 21;9(1):12. doi: 10.1186/s13395-019-0198-x. Skelet Muscle. 2019. PMID: 31113472 Free PMC article.
Insights into pediatric rhabdomyosarcoma research: Challenges and goals.
Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DM. Yohe ME, et al. Among authors: keller c. Pediatr Blood Cancer. 2019 Oct;66(10):e27869. doi: 10.1002/pbc.27869. Epub 2019 Jun 21. Pediatr Blood Cancer. 2019. PMID: 31222885 Free PMC article. Review.
1,872 results