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Maraviroc treatment in non-R5-HIV-1-infected patients results in the selection of extreme CXCR4-using variants with limited effect on the total viral setpoint.
McGovern RA, Symons J, Poon AF, Harrigan PR, van Lelyveld SF, Hoepelman AI, van Ham PM, Dong W, Wensing AM, Nijhuis M. McGovern RA, et al. Among authors: harrigan pr. J Antimicrob Chemother. 2013 Sep;68(9):2007-14. doi: 10.1093/jac/dkt153. Epub 2013 May 14. J Antimicrob Chemother. 2013. PMID: 23677920
Discordance between Etravirine Phenotype and Genotype-Based Predicted Phenotype for Subtype C HIV-1 from First-Line Antiretroviral Therapy Failures in South Africa.
McCormick KD, Penrose KJ, Brumme CJ, Harrigan PR, Viana RV, Mellors JW, Parikh UM, Wallis CL. McCormick KD, et al. Among authors: harrigan pr. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02101-19. doi: 10.1128/AAC.02101-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32071061 Free PMC article.
Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals after First-Line Antiretroviral Therapy Failure in South Africa.
Penrose KJ, Wallis CL, Brumme CJ, Hamanishi KA, Gordon KC, Viana RV, Harrigan PR, Mellors JW, Parikh UM. Penrose KJ, et al. Among authors: harrigan pr. Antimicrob Agents Chemother. 2017 Jan 24;61(2):e01805-16. doi: 10.1128/AAC.01805-16. Print 2017 Feb. Antimicrob Agents Chemother. 2017. PMID: 27895013 Free PMC article.
Genotypic analysis of the V3 region of HIV from virologic nonresponders to maraviroc-containing regimens reveals distinct patterns of failure.
Swenson LC, Chui CK, Brumme CJ, Chan D, Woods CK, Mo T, Dong W, Chapman D, Lewis M, Demarest JF, James I, Portsmouth S, Goodrich J, Heera J, Valdez H, Harrigan PR. Swenson LC, et al. Among authors: harrigan pr. Antimicrob Agents Chemother. 2013 Dec;57(12):6122-30. doi: 10.1128/AAC.01534-13. Epub 2013 Sep 30. Antimicrob Agents Chemother. 2013. PMID: 24080655 Free PMC article. Clinical Trial.
321 results