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A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer.
O'Sullivan D, Dowling P, Joyce H, McAuley E, McCann A, Henry M, McGovern B, Barham P, Kelleher FC, Murphy J, Kennedy S, Swan N, Moriarty M, Clynes M, Larkin A. O'Sullivan D, et al. Among authors: larkin a. Br J Cancer. 2017 Oct 24;117(9):1326-1335. doi: 10.1038/bjc.2017.306. Epub 2017 Sep 7. Br J Cancer. 2017. PMID: 28881357 Free PMC article.
EGFR and HER2 inhibition in pancreatic cancer.
Walsh N, Kennedy S, Larkin A, Corkery B, O'Driscoll L, Clynes M, Crown J, O'Donovan N. Walsh N, et al. Among authors: larkin a. Invest New Drugs. 2013 Jun;31(3):558-66. doi: 10.1007/s10637-012-9891-x. Epub 2012 Oct 18. Invest New Drugs. 2013. PMID: 23076814
Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer.
Dowling P, Pollard D, Larkin A, Henry M, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarty M, O'Brien E, Morgan R, Clynes M. Dowling P, et al. Among authors: larkin a. Mol Biosyst. 2015 Mar;11(3):743-52. doi: 10.1039/c4mb00384e. Epub 2014 Dec 8. Mol Biosyst. 2015. PMID: 25483567
Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify SOX13 to Be Involved in Invasion and Progression of Pancreatic Cancer.
Nelson SR, Roche S, Cotter M, Garcia PA, Reitmeier D, Zollbrecht E, O'Neill F, Clynes M, Doolan P, Medha JP, Swan N, Larkin A, Walsh N. Nelson SR, et al. Among authors: larkin a. J Oncol. 2020 Dec 24;2020:2951921. doi: 10.1155/2020/2951921. eCollection 2020. J Oncol. 2020. PMID: 33424970 Free PMC article.
312 results