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Evaluation of Hepatic Uptake of OATP1B Substrates by Short Term-Cultured Plated Human Hepatocytes: Comparison With Isolated Suspended Hepatocytes.
Yoshikado T, Lee W, Toshimoto K, Morita K, Kiriake A, Chu X, Lee N, Kimoto E, Varma MVS, Kikuchi R, Scialis RJ, Shen H, Ishiguro N, Lotz R, Li AP, Maeda K, Kusuhara H, Sugiyama Y. Yoshikado T, et al. Among authors: toshimoto k. J Pharm Sci. 2021 Jan;110(1):376-387. doi: 10.1016/j.xphs.2020.10.041. Epub 2020 Oct 27. J Pharm Sci. 2021. PMID: 33122051
Improved Prediction of the Drug-Drug Interactions of Pemafibrate Caused by Cyclosporine A and Rifampicin via PBPK Modeling: Consideration of the Albumin-Mediated Hepatic Uptake of Pemafibrate and Inhibition Constants With Preincubation Against OATP1B.
Park JE, Shitara Y, Lee W, Morita S, Sahi J, Toshimoto K, Sugiyama Y. Park JE, et al. Among authors: toshimoto k. J Pharm Sci. 2021 Jan;110(1):517-528. doi: 10.1016/j.xphs.2020.10.016. Epub 2020 Oct 13. J Pharm Sci. 2021. PMID: 33058894
28 results