Katritch V - Search Results

1

Allosteric sodium in class A GPCR signaling.

Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC. Katritch V, et al. Trends Biochem Sci. 2014 May;39(5):233-44. doi: 10.1016/j.tibs.2014.03.002. Epub 2014 Apr 21. Trends Biochem Sci. 2014. PMID: 24767681 Free PMC article.

2

Chiral Me-2-arachidonoyl Glycerols: The First Potent Endocannabinoid Glyceride Templates with Stability to COX-2.

Nikas SP, Ji L, Liu Y, Georgiadis MO, Dopeshwarkar A, Straiker A, Kudalkar S, Sadybekov AV, Dvorakova M, Katritch V, Mackie K, Marnett L, Makriyannis A. Nikas SP, et al. Among authors: katritch v. ACS Med Chem Lett. 2024 May 28;15(6):965-971. doi: 10.1021/acsmedchemlett.4c00175. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894922

3

Structure-Guided Design of Partial Agonists at an Opioid Receptor.

Che T, Varga B, Bernhard SM, El Daibani A, Zaidi S, Lam J, Aguilar J, Appourchaux K, Nazarova A, Kouvelis A, Eans S, Margolis E, Fay J, Pradhan A, Katritch V, McLaughlin J, Majumdar S. Che T, et al. Among authors: katritch v. Res Sq [Preprint]. 2024 Jul 16:rs.3.rs-4664764. doi: 10.21203/rs.3.rs-4664764/v1. Res Sq. 2024. PMID: 39070616 Free PMC article. Preprint.

4

Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D₃ (D₃R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics.

Bonifazi A, Saab E, Sanchez J, Nazarova AL, Zaidi SA, Jahan K, Katritch V, Canals M, Lane JR, Newman AH. Bonifazi A, et al. Among authors: katritch v. J Med Chem. 2023 Aug 10;66(15):10304-10341. doi: 10.1021/acs.jmedchem.3c00417. Epub 2023 Jul 19. J Med Chem. 2023. PMID: 37467430 Free PMC article.

5

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.

Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M. Cherezov V, et al. Among authors: katritch v. Proteins. 2008 Apr;71(1):24-34. doi: 10.1002/prot.21841. Proteins. 2008. PMID: 18076035

6

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.

Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Katritch V, et al. J Mol Recognit. 2009 Jul-Aug;22(4):307-18. doi: 10.1002/jmr.949. J Mol Recognit. 2009. PMID: 19353579 Free PMC article.

7

Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists.

Katritch V, Jaakola VP, Lane JR, Lin J, Ijzerman AP, Yeager M, Kufareva I, Stevens RC, Abagyan R. Katritch V, et al. J Med Chem. 2010 Feb 25;53(4):1799-809. doi: 10.1021/jm901647p. J Med Chem. 2010. PMID: 20095623 Free PMC article.

8

Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

Jaakola VP, Lane JR, Lin JY, Katritch V, Ijzerman AP, Stevens RC. Jaakola VP, et al. Among authors: katritch v. J Biol Chem. 2010 Apr 23;285(17):13032-44. doi: 10.1074/jbc.M109.096974. Epub 2010 Feb 10. J Biol Chem. 2010. PMID: 20147292 Free PMC article.

9

Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.

Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC. Wacker D, et al. Among authors: katritch v. J Am Chem Soc. 2010 Aug 25;132(33):11443-5. doi: 10.1021/ja105108q. J Am Chem Soc. 2010. PMID: 20669948 Free PMC article.

10

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.

Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Wu B, et al. Among authors: katritch v. Science. 2010 Nov 19;330(6007):1066-71. doi: 10.1126/science.1194396. Epub 2010 Oct 7. Science. 2010. PMID: 20929726 Free PMC article.

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