Javier RT - Search Results

1

The human adenovirus E4-ORF1 protein subverts discs large 1 to mediate membrane recruitment and dysregulation of phosphatidylinositol 3-kinase.

Kong K, Kumar M, Taruishi M, Javier RT. Kong K, et al. Among authors: javier rt. PLoS Pathog. 2014 May 1;10(5):e1004102. doi: 10.1371/journal.ppat.1004102. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24788832 Free PMC article.

2

Hijacking Dlg1 for oncogenic phosphatidylinositol 3-kinase activation in human epithelial cells is a conserved mechanism of human adenovirus E4-ORF1 proteins.

Kumar M, Kong K, Javier RT. Kumar M, et al. Among authors: javier rt. J Virol. 2014 Dec;88(24):14268-77. doi: 10.1128/JVI.02324-14. Epub 2014 Sep 24. J Virol. 2014. PMID: 25253337 Free PMC article.

3

Adenovirus E4-ORF1 Dysregulates Epidermal Growth Factor and Insulin/Insulin-Like Growth Factor Receptors To Mediate Constitutive Myc Expression.

Kong K, Kumar M, Taruishi M, Javier RT. Kong K, et al. Among authors: javier rt. J Virol. 2015 Nov;89(21):10774-85. doi: 10.1128/JVI.01463-15. Epub 2015 Aug 12. J Virol. 2015. PMID: 26269183 Free PMC article.

4

High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells.

Irvin-Wilson CV, Newberg JY, Kong K, Javier RT, Marriott SJ. Irvin-Wilson CV, et al. Among authors: javier rt. Viruses. 2011 Dec;3(12):2396-411. doi: 10.3390/v3122396. Epub 2011 Nov 28. Viruses. 2011. PMID: 22355445 Free PMC article.

5

A new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesicles.

Chung SH, Frese KK, Weiss RS, Prasad BV, Javier RT. Chung SH, et al. Among authors: javier rt. J Virol. 2007 May;81(9):4787-97. doi: 10.1128/JVI.02855-06. Epub 2007 Feb 21. J Virol. 2007. PMID: 17314165 Free PMC article.

6

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein.

Lee SS, Weiss RS, Javier RT. Lee SS, et al. Among authors: javier rt. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6670-5. doi: 10.1073/pnas.94.13.6670. Proc Natl Acad Sci U S A. 1997. PMID: 9192623 Free PMC article.

7

A carboxy-terminal region required by the adenovirus type 9 E4 ORF1 oncoprotein for transformation mediates direct binding to cellular polypeptides.

Weiss RS, Javier RT. Weiss RS, et al. Among authors: javier rt. J Virol. 1997 Oct;71(10):7873-80. doi: 10.1128/JVI.71.10.7873-7880.1997. J Virol. 1997. PMID: 9311876 Free PMC article.

8

Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor.

Frese KK, Latorre IJ, Chung SH, Caruana G, Bernstein A, Jones SN, Donehower LA, Justice MJ, Garner CC, Javier RT. Frese KK, et al. Among authors: javier rt. EMBO J. 2006 Mar 22;25(6):1406-17. doi: 10.1038/sj.emboj.7601030. Epub 2006 Mar 2. EMBO J. 2006. PMID: 16511562 Free PMC article.

9

Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins.

Lee SS, Glaunsinger B, Mantovani F, Banks L, Javier RT. Lee SS, et al. Among authors: javier rt. J Virol. 2000 Oct;74(20):9680-93. doi: 10.1128/jvi.74.20.9680-9693.2000. J Virol. 2000. PMID: 11000240 Free PMC article.

10

Mutant adenovirus type 9 E4 ORF1 genes define three protein regions required for transformation of CREF cells.

Weiss RS, Gold MO, Vogel H, Javier RT. Weiss RS, et al. Among authors: javier rt. J Virol. 1997 Jun;71(6):4385-94. doi: 10.1128/JVI.71.6.4385-4394.1997. J Virol. 1997. PMID: 9151828 Free PMC article.

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