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Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.
Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Bermejo JL, Gretz N, Zender L, Schirmacher P, Beck M, Singer S. Winkler J, et al. Among authors: holzer k. Hepatology. 2014 Sep;60(3):884-95. doi: 10.1002/hep.27207. Epub 2014 Jul 17. Hepatology. 2014. PMID: 24799195
Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).
Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S. Winkler J, et al. Among authors: holzer k. Oncotarget. 2016 Apr 19;7(16):22883-92. doi: 10.18632/oncotarget.8256. Oncotarget. 2016. PMID: 27015362 Free PMC article.
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Holzer K, Drucker E, Roessler S, Dauch D, Heinzmann F, Waldburger N, Eiteneuer EM, Herpel E, Breuhahn K, Zender L, Schirmacher P, Ori A, Singer S. Holzer K, et al. Am J Pathol. 2017 Feb;187(2):228-235. doi: 10.1016/j.ajpath.2016.09.022. Epub 2016 Dec 7. Am J Pathol. 2017. PMID: 27939741 Free article.
Nucleoporin Nup155 is part of the p53 network in liver cancer.
Holzer K, Ori A, Cooke A, Dauch D, Drucker E, Riemenschneider P, Andres-Pons A, DiGuilio AL, Mackmull MT, Baßler J, Roessler S, Breuhahn K, Zender L, Glavy JS, Dombrowski F, Hurt E, Schirmacher P, Beck M, Singer S. Holzer K, et al. Nat Commun. 2019 May 14;10(1):2147. doi: 10.1038/s41467-019-10133-z. Nat Commun. 2019. PMID: 31089132 Free PMC article.
Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).
Buczak K, Ori A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer S, Beck M. Buczak K, et al. Among authors: holzer k. Mol Cell Proteomics. 2018 Apr;17(4):810-825. doi: 10.1074/mcp.RA117.000189. Epub 2018 Jan 23. Mol Cell Proteomics. 2018. PMID: 29363612 Free PMC article.
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.
Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V. Krishna-Subramanian S, et al. Among authors: holzer k. Cell Death Differ. 2019 Dec;26(12):2710-2726. doi: 10.1038/s41418-019-0330-9. Epub 2019 Apr 15. Cell Death Differ. 2019. PMID: 30988397 Free PMC article.
219 results