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Priming of microglia in a DNA-repair deficient model of accelerated aging.
Raj DD, Jaarsma D, Holtman IR, Olah M, Ferreira FM, Schaafsma W, Brouwer N, Meijer MM, de Waard MC, van der Pluijm I, Brandt R, Kreft KL, Laman JD, de Haan G, Biber KP, Hoeijmakers JH, Eggen BJ, Boddeke HW. Raj DD, et al. Among authors: brandt r. Neurobiol Aging. 2014 Sep;35(9):2147-60. doi: 10.1016/j.neurobiolaging.2014.03.025. Epub 2014 Mar 28. Neurobiol Aging. 2014. PMID: 24799273 Free article.
Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
van der Pluijm I, Garinis GA, Brandt RM, Gorgels TG, Wijnhoven SW, Diderich KE, de Wit J, Mitchell JR, van Oostrom C, Beems R, Niedernhofer LJ, Velasco S, Friedberg EC, Tanaka K, van Steeg H, Hoeijmakers JH, van der Horst GT. van der Pluijm I, et al. Among authors: brandt rm. PLoS Biol. 2007 Jan;5(1):e2. doi: 10.1371/journal.pbio.0050002. PLoS Biol. 2007. PMID: 17326724 Free PMC article.
Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.
Jaarsma D, van der Pluijm I, de Waard MC, Haasdijk ED, Brandt R, Vermeij M, Rijksen Y, Maas A, van Steeg H, Hoeijmakers JH, van der Horst GT. Jaarsma D, et al. Among authors: brandt r. PLoS Genet. 2011 Dec;7(12):e1002405. doi: 10.1371/journal.pgen.1002405. Epub 2011 Dec 8. PLoS Genet. 2011. PMID: 22174697 Free PMC article.
Nucleotide excision DNA repair is associated with age-related vascular dysfunction.
Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, van Deel ED, de Boer M, Tempel D, Fleming I, Mitchell GF, Verwoert GC, Tarasov KV, Uitterlinden AG, Hofman A, Duckers HJ, van Duijn CM, Oostra BA, Witteman JC, Duncker DJ, Danser AH, Hoeijmakers JH, Roks AJ. Durik M, et al. Among authors: brandt r. Circulation. 2012 Jul 24;126(4):468-78. doi: 10.1161/CIRCULATIONAHA.112.104380. Epub 2012 Jun 15. Circulation. 2012. PMID: 22705887 Free PMC article.
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.
Barnhoorn S, Uittenboogaard LM, Jaarsma D, Vermeij WP, Tresini M, Weymaere M, Menoni H, Brandt RM, de Waard MC, Botter SM, Sarker AH, Jaspers NG, van der Horst GT, Cooper PK, Hoeijmakers JH, van der Pluijm I. Barnhoorn S, et al. PLoS Genet. 2014 Oct 9;10(10):e1004686. doi: 10.1371/journal.pgen.1004686. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25299392 Free PMC article.
Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.
Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, de Waard MC, de Krijger RR, Boelen A, Kwakkel J, Kopchick JJ, List EO, Melis JP, Darras VM, Dollé ME, van der Horst GT, Hoeijmakers JH, Visser TJ. Visser WE, et al. Among authors: brandt r. PLoS One. 2016 Mar 8;11(3):e0149941. doi: 10.1371/journal.pone.0149941. eCollection 2016. PLoS One. 2016. PMID: 26953569 Free PMC article.
799 results