Gygi S - Search Results

1

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL. Besche HC, et al. Among authors: gygi s. EMBO J. 2014 May 16;33(10):1159-76. doi: 10.1002/embj.201386906. Epub 2014 May 8. EMBO J. 2014. PMID: 24811749 Free PMC article.

2

The ubiquitin-proteasome system regulates membrane fusion of yeast vacuoles.

Kleijnen MF, Kirkpatrick DS, Gygi SP. Kleijnen MF, et al. Among authors: gygi sp. EMBO J. 2007 Jan 24;26(2):275-87. doi: 10.1038/sj.emboj.7601486. Epub 2006 Dec 21. EMBO J. 2007. PMID: 17183369 Free PMC article.

3

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

Crosas B, Hanna J, Kirkpatrick DS, Zhang DP, Tone Y, Hathaway NA, Buecker C, Leggett DS, Schmidt M, King RW, Gygi SP, Finley D. Crosas B, et al. Among authors: gygi sp. Cell. 2006 Dec 29;127(7):1401-13. doi: 10.1016/j.cell.2006.09.051. Cell. 2006. PMID: 17190603 Free article.

4

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL. Kim HT, et al. J Biol Chem. 2007 Jun 15;282(24):17375-86. doi: 10.1074/jbc.M609659200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426036 Free article.

5

Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.

Matiuhin Y, Kirkpatrick DS, Ziv I, Kim W, Dakshinamurthy A, Kleifeld O, Gygi SP, Reis N, Glickman MH. Matiuhin Y, et al. Among authors: gygi sp. Mol Cell. 2008 Nov 7;32(3):415-25. doi: 10.1016/j.molcel.2008.10.011. Mol Cell. 2008. PMID: 18995839 Free PMC article.

6

Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins.

Besche HC, Haas W, Gygi SP, Goldberg AL. Besche HC, et al. Biochemistry. 2009 Mar 24;48(11):2538-49. doi: 10.1021/bi802198q. Biochemistry. 2009. PMID: 19182904 Free PMC article.

7

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.

Uchiki T, Kim HT, Zhai B, Gygi SP, Johnston JA, O'Bryan JP, Goldberg AL. Uchiki T, et al. J Biol Chem. 2009 May 8;284(19):12622-32. doi: 10.1074/jbc.M900556200. Epub 2009 Feb 24. J Biol Chem. 2009. PMID: 19240029 Free PMC article.

8

S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains.

Kim HT, Kim KP, Uchiki T, Gygi SP, Goldberg AL. Kim HT, et al. EMBO J. 2009 Jul 8;28(13):1867-77. doi: 10.1038/emboj.2009.115. Epub 2009 Apr 23. EMBO J. 2009. PMID: 19387488 Free PMC article.

9

Hexameric assembly of the proteasomal ATPases is templated through their C termini.

Park S, Roelofs J, Kim W, Robert J, Schmidt M, Gygi SP, Finley D. Park S, et al. Among authors: gygi sp. Nature. 2009 Jun 11;459(7248):866-70. doi: 10.1038/nature08065. Nature. 2009. PMID: 19412160 Free PMC article.

10

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

Cohen S, Brault JJ, Gygi SP, Glass DJ, Valenzuela DM, Gartner C, Latres E, Goldberg AL. Cohen S, et al. Among authors: gygi sp. J Cell Biol. 2009 Jun 15;185(6):1083-95. doi: 10.1083/jcb.200901052. Epub 2009 Jun 8. J Cell Biol. 2009. PMID: 19506036 Free PMC article.

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