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Page 1
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
Colak E, Leslie A, Zausmer K, Khatamzas E, Kubarenko AV, Pichulik T, Klimosch SN, Mayer A, Siggs O, Hector A, Fischer R, Klesser B, Rautanen A, Frank M, Hill AV, Manoury B, Beutler B, Hartl D, Simmons A, Weber AN. Colak E, et al. Among authors: beutler b. J Immunol. 2014 Jun 15;192(12):5963-73. doi: 10.4049/jimmunol.1303058. Epub 2014 May 9. J Immunol. 2014. PMID: 24813206 Free PMC article.
Genetic analysis of innate immunity.
Hoebe K, Jiang Z, Tabeta K, Du X, Georgel P, Crozat K, Beutler B. Hoebe K, et al. Among authors: beutler b. Adv Immunol. 2006;91:175-226. doi: 10.1016/S0065-2776(06)91005-0. Adv Immunol. 2006. PMID: 16938541 Review.
Cutting edge: Priming of NK cells by IL-18.
Chaix J, Tessmer MS, Hoebe K, Fuséri N, Ryffel B, Dalod M, Alexopoulou L, Beutler B, Brossay L, Vivier E, Walzer T. Chaix J, et al. Among authors: beutler b. J Immunol. 2008 Aug 1;181(3):1627-31. doi: 10.4049/jimmunol.181.3.1627. J Immunol. 2008. PMID: 18641298 Free PMC article.
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. Siggs OM, et al. Among authors: beutler b. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3046-51. doi: 10.1073/pnas.0915098107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133626 Free PMC article.
Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice.
Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, Hildeman D, Grimes HL, Beutler B, Hoebe K. Barnes MJ, et al. Among authors: beutler b. J Immunol. 2010 Apr 1;184(7):3743-54. doi: 10.4049/jimmunol.0903164. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190135 Free PMC article.
525 results