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499 results

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Page 1
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
Colak E, Leslie A, Zausmer K, Khatamzas E, Kubarenko AV, Pichulik T, Klimosch SN, Mayer A, Siggs O, Hector A, Fischer R, Klesser B, Rautanen A, Frank M, Hill AV, Manoury B, Beutler B, Hartl D, Simmons A, Weber AN. Colak E, et al. Among authors: leslie a. J Immunol. 2014 Jun 15;192(12):5963-73. doi: 10.4049/jimmunol.1303058. Epub 2014 May 9. J Immunol. 2014. PMID: 24813206 Free PMC article.
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.
Brain O, Owens BM, Pichulik T, Allan P, Khatamzas E, Leslie A, Steevels T, Sharma S, Mayer A, Catuneanu AM, Morton V, Sun MY, Jewell D, Coccia M, Harrison O, Maloy K, Schönefeldt S, Bornschein S, Liston A, Simmons A. Brain O, et al. Among authors: leslie a. Immunity. 2013 Sep 19;39(3):521-36. doi: 10.1016/j.immuni.2013.08.035. Immunity. 2013. PMID: 24054330 Free article.
Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus.
Pichulik T, Khatamzas E, Liu X, Brain O, Delmiro Garcia M, Leslie A, Danis B, Mayer A, Baban D, Ragoussis J, Weber AN, Simmons A. Pichulik T, et al. Among authors: leslie a. Eur J Immunol. 2016 Jan;46(1):167-77. doi: 10.1002/eji.201444970. Epub 2015 Oct 30. Eur J Immunol. 2016. PMID: 26460926 Free PMC article.
Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.
Khatamzas E, Hipp MM, Gaughan D, Pichulik T, Leslie A, Fernandes RA, Muraro D, Booth S, Zausmer K, Sun MY, Kessler B, Rowland-Jones S, Cerundolo V, Simmons A. Khatamzas E, et al. Among authors: leslie a. EMBO J. 2017 Oct 16;36(20):2998-3011. doi: 10.15252/embj.201695364. Epub 2017 Sep 18. EMBO J. 2017. PMID: 28923824 Free PMC article.
HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.
Matthews PC, Adland E, Listgarten J, Leslie A, Mkhwanazi N, Carlson JM, Harndahl M, Stryhn A, Payne RP, Ogwu A, Huang KH, Frater J, Paioni P, Kloverpris H, Jooste P, Goedhals D, van Vuuren C, Steyn D, Riddell L, Chen F, Luzzi G, Balachandran T, Ndung'u T, Buus S, Carrington M, Shapiro R, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: leslie a. J Immunol. 2011 May 15;186(10):5675-86. doi: 10.4049/jimmunol.1003711. Epub 2011 Apr 15. J Immunol. 2011. PMID: 21498667 Free PMC article.
Structure and interactions of the human programmed cell death 1 receptor.
Cheng X, Veverka V, Radhakrishnan A, Waters LC, Muskett FW, Morgan SH, Huo J, Yu C, Evans EJ, Leslie AJ, Griffiths M, Stubberfield C, Griffin R, Henry AJ, Jansson A, Ladbury JE, Ikemizu S, Carr MD, Davis SJ. Cheng X, et al. Among authors: leslie aj. J Biol Chem. 2013 Apr 26;288(17):11771-85. doi: 10.1074/jbc.M112.448126. Epub 2013 Feb 15. J Biol Chem. 2013. PMID: 23417675 Free PMC article.
Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
Leslie A, Price DA, Mkhize P, Bishop K, Rathod A, Day C, Crawford H, Honeyborne I, Asher TE, Luzzi G, Edwards A, Rousseau CM, Mullins JI, Tudor-Williams G, Novelli V, Brander C, Douek DC, Kiepiela P, Walker BD, Goulder PJ. Leslie A, et al. J Immunol. 2006 Oct 1;177(7):4699-708. doi: 10.4049/jimmunol.177.7.4699. J Immunol. 2006. PMID: 16982909
CD8+ TCR Bias and Immunodominance in HIV-1 Infection.
Kløverpris HN, McGregor R, McLaren JE, Ladell K, Harndahl M, Stryhn A, Carlson JM, Koofhethile C, Gerritsen B, Keşmir C, Chen F, Riddell L, Luzzi G, Leslie A, Walker BD, Ndung'u T, Buus S, Price DA, Goulder PJ. Kløverpris HN, et al. Among authors: leslie a. J Immunol. 2015 Jun 1;194(11):5329-45. doi: 10.4049/jimmunol.1400854. Epub 2015 Apr 24. J Immunol. 2015. PMID: 25911754 Free PMC article.
Tissue-resident innate immunity in the lung.
Ardain A, Marakalala MJ, Leslie A. Ardain A, et al. Among authors: leslie a. Immunology. 2020 Mar;159(3):245-256. doi: 10.1111/imm.13143. Epub 2019 Nov 21. Immunology. 2020. PMID: 31670391 Free PMC article. Review.
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: leslie aj. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384
499 results