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164 results

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Page 1
In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.
Postmus I, Johnson PC, Trompet S, de Craen AJ, Slagboom PE, Devlin JJ, Shiffman D, Sacks FM, Kearney PM, Stott DJ, Buckley BM, Sattar N, Ford I, Westendorp RG, Jukema JW. Postmus I, et al. Among authors: buckley bm. Atherosclerosis. 2014 Jul;235(1):58-64. doi: 10.1016/j.atherosclerosis.2014.04.009. Epub 2014 Apr 26. Atherosclerosis. 2014. PMID: 24816038 Clinical Trial.
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
Polisecki E, Muallem H, Maeda N, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Westendorp RG, de Craen AJ, Buckley BM, Ordovas JM, Schaefer EJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators. Polisecki E, et al. Among authors: buckley bm. Atherosclerosis. 2008 Sep;200(1):109-14. doi: 10.1016/j.atherosclerosis.2007.12.004. Epub 2008 Feb 7. Atherosclerosis. 2008. PMID: 18261733 Free PMC article. Clinical Trial.
Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.
Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group. Polisecki E, et al. Among authors: buckley bm. Atherosclerosis. 2008 Sep;200(1):95-101. doi: 10.1016/j.atherosclerosis.2007.12.005. Epub 2008 Feb 8. Atherosclerosis. 2008. PMID: 18262190 Free PMC article. Clinical Trial.
Pravastatin and cognitive function in the elderly. Results of the PROSPER study.
Trompet S, van Vliet P, de Craen AJ, Jolles J, Buckley BM, Murphy MB, Ford I, Macfarlane PW, Sattar N, Packard CJ, Stott DJ, Shepherd J, Bollen EL, Blauw GJ, Jukema JW, Westendorp RG. Trompet S, et al. Among authors: buckley bm. J Neurol. 2010 Jan;257(1):85-90. doi: 10.1007/s00415-009-5271-7. Epub 2009 Aug 4. J Neurol. 2010. PMID: 19653027 Clinical Trial.
Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly.
Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. Akao H, et al. Among authors: buckley bm. Atherosclerosis. 2012 Feb;220(2):413-7. doi: 10.1016/j.atherosclerosis.2011.09.028. Epub 2011 Sep 21. Atherosclerosis. 2012. PMID: 22189199 Clinical Trial.
KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.
Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. Akao H, et al. Among authors: buckley bm. Atherosclerosis. 2012 Feb;220(2):456-62. doi: 10.1016/j.atherosclerosis.2011.11.037. Epub 2011 Dec 7. Atherosclerosis. 2012. PMID: 22192511 Clinical Trial.
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy.
Shiffman D, Trompet S, Louie JZ, Rowland CM, Catanese JJ, Iakoubova OA, Kirchgessner TG, Westendorp RG, de Craen AJ, Slagboom PE, Buckley BM, Stott DJ, Sattar N, Devlin JJ, Packard CJ, Ford I, Sacks FM, Jukema JW. Shiffman D, et al. Among authors: buckley bm. PLoS One. 2012;7(5):e38240. doi: 10.1371/journal.pone.0038240. Epub 2012 May 30. PLoS One. 2012. PMID: 22666496 Free PMC article. Clinical Trial.
164 results