Laufer SA - Search Results

1

2-(3-{(3R,4R)-4-Methyl-3-[meth-yl(7H-pyrrolo-[2,3-d]pyrimidin-4-yl)amino]-piperidin-1-yl}oxetan-3-yl)aceto-nitrile monohydrate.

Gehringer M, Pfaffenrot E, Keck PR, Schollmeyer D, Laufer SA. Gehringer M, et al. Among authors: laufer sa. Acta Crystallogr Sect E Struct Rep Online. 2014 Mar 5;70(Pt 4):o382-3. doi: 10.1107/S1600536814004449. eCollection 2014 Apr 1. Acta Crystallogr Sect E Struct Rep Online. 2014. PMID: 24826108 Free PMC article.

2

From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.

Peifer C, Kinkel K, Abadleh M, Schollmeyer D, Laufer S. Peifer C, et al. J Med Chem. 2007 Mar 22;50(6):1213-21. doi: 10.1021/jm061097o. Epub 2007 Feb 27. J Med Chem. 2007. PMID: 17323937

3

Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors.

Peifer C, Selig R, Kinkel K, Ott D, Totzke F, Schächtele C, Heidenreich R, Röcken M, Schollmeyer D, Laufer S. Peifer C, et al. J Med Chem. 2008 Jul 10;51(13):3814-24. doi: 10.1021/jm8001185. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18529047

4

Arylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) or as dual inhibitors of mPGES-1 and 5-lipoxygenase (5-LOX).

Liedtke AJ, Keck PR, Lehmann F, Koeberle A, Werz O, Laufer SA. Liedtke AJ, et al. Among authors: laufer sa. J Med Chem. 2009 Aug 13;52(15):4968-72. doi: 10.1021/jm900481c. J Med Chem. 2009. PMID: 19719242

5

4-[4-(4-Fluoro-phen-yl)-2-methyl-5-oxo-2,5-dihydro-isoxazol-3-yl]-1-methyl-pyridinium iodide-4-[3-(4-fluoro-phen-yl)-2-methyl-5-oxo-2,5-dihydro-isoxazol-4-yl]-1-methyl-pyridinium iodide (0.6/0.4).

Margutti S, Schollmeyer D, Laufer S. Margutti S, et al. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 18;64(Pt 1):o298-9. doi: 10.1107/S1600536807055985. Acta Crystallogr Sect E Struct Rep Online. 2007. PMID: 21200862 Free PMC article.

6

4-(4-Fluoro-phen-yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one.

Margutti S, Schollmeyer D, Laufer S. Margutti S, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 23;64(Pt 2):o504. doi: 10.1107/S1600536807066500. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21201524 Free PMC article.

7

3-(2-Fluoro-phen-yl)-6-(phenoxy-meth-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

Holm M, Schollmeyer D, Laufer S. Holm M, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Mar 12;64(Pt 4):o700. doi: 10.1107/S1600536808003917. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202091 Free PMC article.

8

6-Amino-1-benzyl-4-(4-chloro-phen-yl)-3-(4-pyrid-yl)-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile.

Lehmann F, Schollmeyer D, Laufer S. Lehmann F, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Mar 12;64(Pt 4):o701. doi: 10.1107/S160053680800487X. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202092 Free PMC article.

9

Methyl 4-[5-(4-fluoro-phen-yl)-4-(pyridin-4-yl)-1H-imidazol-2-ylsulfan-yl]butanoate.

Koch P, Bäuerlein C, Schollmeyer D, Laufer S. Koch P, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 7;64(Pt 7):o1183-4. doi: 10.1107/S1600536808016000. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202826 Free PMC article.

10

Chiral sulfoxides as metabolites of 2-thioimidazole-based p38α mitogen-activated protein kinase inhibitors: enantioselective synthesis and biological evaluation.

Bühler S, Goettert M, Schollmeyer D, Albrecht W, Laufer SA. Bühler S, et al. Among authors: laufer sa. J Med Chem. 2011 May 12;54(9):3283-97. doi: 10.1021/jm101623p. Epub 2011 Apr 12. J Med Chem. 2011. PMID: 21449619

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