Steinbacher J - Search Results

1

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.

Pfaffeneder T, Spada F, Wagner M, Brandmayr C, Laube SK, Eisen D, Truss M, Steinbacher J, Hackner B, Kotljarova O, Schuermann D, Michalakis S, Kosmatchev O, Schiesser S, Steigenberger B, Raddaoui N, Kashiwazaki G, Müller U, Spruijt CG, Vermeulen M, Leonhardt H, Schär P, Müller M, Carell T. Pfaffeneder T, et al. Among authors: steinbacher j. Nat Chem Biol. 2014 Jul;10(7):574-81. doi: 10.1038/nchembio.1532. Epub 2014 May 18. Nat Chem Biol. 2014. PMID: 24838012

2

Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine.

Schiesser S, Pfaffeneder T, Sadeghian K, Hackner B, Steigenberger B, Schröder AS, Steinbacher J, Kashiwazaki G, Höfner G, Wanner KT, Ochsenfeld C, Carell T. Schiesser S, et al. Among authors: steinbacher j. J Am Chem Soc. 2013 Oct 2;135(39):14593-9. doi: 10.1021/ja403229y. Epub 2013 Sep 17. J Am Chem Soc. 2013. PMID: 23980549

3

Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.

Wagner M, Steinbacher J, Kraus TF, Michalakis S, Hackner B, Pfaffeneder T, Perera A, Müller M, Giese A, Kretzschmar HA, Carell T. Wagner M, et al. Among authors: steinbacher j. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12511-4. doi: 10.1002/anie.201502722. Epub 2015 Jul 3. Angew Chem Int Ed Engl. 2015. PMID: 26137924 Free PMC article.

4

5-Formylcytosine to cytosine conversion by C-C bond cleavage in vivo.

Iwan K, Rahimoff R, Kirchner A, Spada F, Schröder AS, Kosmatchev O, Ferizaj S, Steinbacher J, Parsa E, Müller M, Carell T. Iwan K, et al. Among authors: steinbacher j. Nat Chem Biol. 2018 Jan;14(1):72-78. doi: 10.1038/nchembio.2531. Epub 2017 Nov 27. Nat Chem Biol. 2018. PMID: 29176672

5

Synthesis of 5-hydroxymethyl-, 5-formyl-, and 5-carboxycytidine-triphosphates and their incorporation into oligonucleotides by polymerase chain reaction.

Steigenberger B, Schiesser S, Hackner B, Brandmayr C, Laube SK, Steinbacher J, Pfaffeneder T, Carell T. Steigenberger B, et al. Among authors: steinbacher j. Org Lett. 2013 Jan 18;15(2):366-9. doi: 10.1021/ol3033219. Epub 2013 Jan 3. Org Lett. 2013. PMID: 23286330

6

Synthesis of a DNA promoter segment containing all four epigenetic nucleosides: 5-methyl-, 5-hydroxymethyl-, 5-formyl-, and 5-carboxy-2'-deoxycytidine.

Schröder AS, Steinbacher J, Steigenberger B, Gnerlich FA, Schiesser S, Pfaffeneder T, Carell T. Schröder AS, et al. Among authors: steinbacher j. Angew Chem Int Ed Engl. 2014 Jan 3;53(1):315-8. doi: 10.1002/anie.201308469. Epub 2013 Nov 26. Angew Chem Int Ed Engl. 2014. PMID: 24281791

7

TET3 is recruited by REST for context-specific hydroxymethylation and induction of gene expression.

Perera A, Eisen D, Wagner M, Laube SK, Künzel AF, Koch S, Steinbacher J, Schulze E, Splith V, Mittermeier N, Müller M, Biel M, Carell T, Michalakis S. Perera A, et al. Among authors: steinbacher j. Cell Rep. 2015 Apr 14;11(2):283-94. doi: 10.1016/j.celrep.2015.03.020. Epub 2015 Apr 2. Cell Rep. 2015. PMID: 25843715 Free article.

8

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Peng Koh K, Mazzone M, Coleman M, Carell T, Carmeliet P, Lambrechts D. Thienpont B, et al. Among authors: steinbacher j. Nature. 2016 Sep 1;537(7618):63-68. doi: 10.1038/nature19081. Epub 2016 Aug 17. Nature. 2016. PMID: 27533040 Free PMC article.

9

Quantitative LC-MS Provides No Evidence for m⁶ dA or m⁴ dC in the Genome of Mouse Embryonic Stem Cells and Tissues.

Schiffers S, Ebert C, Rahimoff R, Kosmatchev O, Steinbacher J, Bohne AV, Spada F, Michalakis S, Nickelsen J, Müller M, Carell T. Schiffers S, et al. Among authors: steinbacher j. Angew Chem Int Ed Engl. 2017 Sep 4;56(37):11268-11271. doi: 10.1002/anie.201700424. Epub 2017 Mar 30. Angew Chem Int Ed Engl. 2017. PMID: 28371147

10

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine.

Gassen NC, Fries GR, Zannas AS, Hartmann J, Zschocke J, Hafner K, Carrillo-Roa T, Steinbacher J, Preißinger SN, Hoeijmakers L, Knop M, Weber F, Kloiber S, Lucae S, Chrousos GP, Carell T, Ising M, Binder EB, Schmidt MV, Rüegg J, Rein T. Gassen NC, et al. Among authors: steinbacher j. Sci Signal. 2015 Nov 24;8(404):ra119. doi: 10.1126/scisignal.aac7695. Sci Signal. 2015. PMID: 26602018

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