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Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Richter F, Gao F, Medvedeva V, Lee P, Bove N, Fleming SM, Michaud M, Lemesre V, Patassini S, De La Rosa K, Mulligan CK, Sioshansi PC, Zhu C, Coppola G, Bordet T, Pruss RM, Chesselet MF. Richter F, et al. Among authors: gao f. Neurobiol Dis. 2014 Sep;69:263-75. doi: 10.1016/j.nbd.2014.05.012. Epub 2014 May 18. Neurobiol Dis. 2014. PMID: 24844147 Free PMC article.
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. Thomas EA, et al. Among authors: gao f. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15564-9. doi: 10.1073/pnas.0804249105. Epub 2008 Sep 30. Proc Natl Acad Sci U S A. 2008. PMID: 18829438 Free PMC article.
A gene expression phenotype in lymphocytes from Friedreich ataxia patients.
Coppola G, Burnett R, Perlman S, Versano R, Gao F, Plasterer H, Rai M, Saccá F, Filla A, Lynch DR, Rusche JR, Gottesfeld JM, Pandolfo M, Geschwind DH. Coppola G, et al. Among authors: gao f. Ann Neurol. 2011 Nov;70(5):790-804. doi: 10.1002/ana.22526. Ann Neurol. 2011. PMID: 22162061 Free PMC article.
An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.
Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind MD, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G. Li Y, et al. Among authors: gao f. PLoS Genet. 2014 Mar 6;10(3):e1004211. doi: 10.1371/journal.pgen.1004211. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24603599 Free PMC article.
Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.
Fogel BL, Cho E, Wahnich A, Gao F, Becherel OJ, Wang X, Fike F, Chen L, Criscuolo C, De Michele G, Filla A, Collins A, Hahn AF, Gatti RA, Konopka G, Perlman S, Lavin MF, Geschwind DH, Coppola G. Fogel BL, et al. Among authors: gao f. Hum Mol Genet. 2014 Sep 15;23(18):4758-69. doi: 10.1093/hmg/ddu190. Epub 2014 Apr 23. Hum Mol Genet. 2014. PMID: 24760770 Free PMC article.
Novel candidate blood-based transcriptional biomarkers of Machado-Joseph disease.
Raposo M, Bettencourt C, Maciel P, Gao F, Ramos A, Kazachkova N, Vasconcelos J, Kay T, Rodrigues AJ, Bettencourt B, Bruges-Armas J, Geschwind D, Coppola G, Lima M. Raposo M, et al. Among authors: gao f. Mov Disord. 2015 Jun;30(7):968-75. doi: 10.1002/mds.26238. Epub 2015 Apr 25. Mov Disord. 2015. PMID: 25914309
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