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Page 1
Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R, Cannas V, Distinto S, Sarais G, Del Vecchio C, Esposito F, Bianco G, Corona A, Cottiglia F, Alcaro S, Parolin C, Artese A, Scalise D, Fresta M, Arridu A, Ortuso F, Maccioni E, Tramontano E. Meleddu R, et al. Among authors: bianco g. ChemMedChem. 2014 Aug;9(8):1869-79. doi: 10.1002/cmdc.201402015. Epub 2014 May 21. ChemMedChem. 2014. PMID: 24850787
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R, Distinto S, Corona A, Bianco G, Cannas V, Esposito F, Artese A, Alcaro S, Matyus P, Bogdan D, Cottiglia F, Tramontano E, Maccioni E. Meleddu R, et al. Among authors: bianco g. Eur J Med Chem. 2015 Mar 26;93:452-60. doi: 10.1016/j.ejmech.2015.02.032. Epub 2015 Feb 20. Eur J Med Chem. 2015. PMID: 25728026
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold.
Distinto S, Meleddu R, Yanez M, Cirilli R, Bianco G, Sanna ML, Arridu A, Cossu P, Cottiglia F, Faggi C, Ortuso F, Alcaro S, Maccioni E. Distinto S, et al. Among authors: bianco g. Eur J Med Chem. 2016 Jan 27;108:542-552. doi: 10.1016/j.ejmech.2015.12.026. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26717204
Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
Corona A, Meleddu R, Esposito F, Distinto S, Bianco G, Masaoka T, Maccioni E, Menéndez-Arias L, Alcaro S, Le Grice SF, Tramontano E. Corona A, et al. Among authors: bianco g. PLoS One. 2016 Jan 22;11(1):e0147225. doi: 10.1371/journal.pone.0147225. eCollection 2016. PLoS One. 2016. PMID: 26800261 Free PMC article.
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R, Distinto S, Corona A, Tramontano E, Bianco G, Melis C, Cottiglia F, Maccioni E. Meleddu R, et al. Among authors: bianco g. J Enzyme Inhib Med Chem. 2017 Dec;32(1):130-136. doi: 10.1080/14756366.2016.1238366. Epub 2016 Oct 21. J Enzyme Inhib Med Chem. 2017. PMID: 27766892 Free PMC article.
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors.
Melis C, Meleddu R, Angeli A, Distinto S, Bianco G, Capasso C, Cottiglia F, Angius R, Supuran CT, Maccioni E. Melis C, et al. Among authors: bianco g. J Enzyme Inhib Med Chem. 2017 Dec;32(1):68-73. doi: 10.1080/14756366.2016.1235042. Epub 2016 Oct 24. J Enzyme Inhib Med Chem. 2017. PMID: 27775452 Free PMC article.
693 results