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Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC. Moreira DR, et al. J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23167554
2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity.
Cardoso MVO, Oliveira Filho GB, Siqueira LRP, Espíndola JWP, Silva EBD, Mendes APO, Pereira VRA, Castro MCAB, Ferreira RS, Villela FS, Costa FMRD, Meira CS, Moreira DRM, Soares MBP, Leite ACL. Cardoso MVO, et al. Eur J Med Chem. 2019 Oct 15;180:191-203. doi: 10.1016/j.ejmech.2019.07.018. Epub 2019 Jul 7. Eur J Med Chem. 2019. PMID: 31306906
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.
Espíndola JW, Cardoso MV, Filho GB, Oliveira E Silva DA, Moreira DR, Bastos TM, Simone CA, Soares MB, Villela FS, Ferreira RS, Castro MC, Pereira VR, Murta SM, Sales Junior PA, Romanha AJ, Leite AC. Espíndola JW, et al. Among authors: moreira dr. Eur J Med Chem. 2015 Aug 28;101:818-35. doi: 10.1016/j.ejmech.2015.06.048. Epub 2015 Jul 3. Eur J Med Chem. 2015. PMID: 26231082
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
Gomes PA, Oliveira AR, Cardoso MV, Santiago Ede F, Barbosa Mde O, de Siqueira LR, Moreira DR, Bastos TM, Brayner FA, Soares MB, Mendes AP, de Castro MC, Pereira VR, Leite AC. Gomes PA, et al. Among authors: moreira dr. Eur J Med Chem. 2016 Mar 23;111:46-57. doi: 10.1016/j.ejmech.2016.01.010. Epub 2016 Jan 11. Eur J Med Chem. 2016. PMID: 26854377
94 results