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Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
Zhang L, Chen LH, Wan H, Yang R, Wang Z, Feng J, Yang S, Jones S, Wang S, Zhou W, Zhu H, Killela PJ, Zhang J, Wu Z, Li G, Hao S, Wang Y, Webb JB, Friedman HS, Friedman AH, McLendon RE, He Y, Reitman ZJ, Bigner DD, Yan H. Zhang L, et al. Among authors: wang z, wang y, wang s. Nat Genet. 2014 Jul;46(7):726-30. doi: 10.1038/ng.2995. Epub 2014 Jun 1. Nat Genet. 2014. PMID: 24880341 Free PMC article.
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas.
Killela PJ, Pirozzi CJ, Healy P, Reitman ZJ, Lipp E, Rasheed BA, Yang R, Diplas BH, Wang Z, Greer PK, Zhu H, Wang CY, Carpenter AB, Friedman H, Friedman AH, Keir ST, He J, He Y, McLendon RE, Herndon JE 2nd, Yan H, Bigner DD. Killela PJ, et al. Among authors: wang z, wang cy. Oncotarget. 2014 Mar 30;5(6):1515-25. doi: 10.18632/oncotarget.1765. Oncotarget. 2014. PMID: 24722048 Free PMC article.
Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.
Waitkus MS, Pirozzi CJ, Moure CJ, Diplas BH, Hansen LJ, Carpenter AB, Yang R, Wang Z, Ingram BO, Karoly ED, Mohney RP, Spasojevic I, McLendon RE, Friedman HS, He Y, Bigner DD, Yan H. Waitkus MS, et al. Among authors: wang z. Cancer Res. 2018 Jan 1;78(1):36-50. doi: 10.1158/0008-5472.CAN-17-1352. Epub 2017 Nov 2. Cancer Res. 2018. PMID: 29097607 Free PMC article.
The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.
Diplas BH, He X, Brosnan-Cashman JA, Liu H, Chen LH, Wang Z, Moure CJ, Killela PJ, Loriaux DB, Lipp ES, Greer PK, Yang R, Rizzo AJ, Rodriguez FJ, Friedman AH, Friedman HS, Wang S, He Y, McLendon RE, Bigner DD, Jiao Y, Waitkus MS, Meeker AK, Yan H. Diplas BH, et al. Among authors: wang z, wang s. Nat Commun. 2018 May 25;9(1):2087. doi: 10.1038/s41467-018-04448-6. Nat Commun. 2018. PMID: 29802247 Free PMC article.
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
Huang DS, Wang Z, He XJ, Diplas BH, Yang R, Killela PJ, Meng Q, Ye ZY, Wang W, Jiang XT, Xu L, He XL, Zhao ZS, Xu WJ, Wang HJ, Ma YY, Xia YJ, Li L, Zhang RX, Jin T, Zhao ZK, Xu J, Yu S, Wu F, Liang J, Wang S, Jiao Y, Yan H, Tao HQ. Huang DS, et al. Among authors: wang w, wang z, wang hj, wang s. Eur J Cancer. 2015 May;51(8):969-76. doi: 10.1016/j.ejca.2015.03.010. Epub 2015 Apr 2. Eur J Cancer. 2015. PMID: 25843513 Free PMC article.
Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors.
Xu C, Liu X, Geng Y, Bai Q, Pan C, Sun Y, Chen X, Yu H, Wu Y, Zhang P, Wu W, Wang Y, Wu Z, Zhang J, Wang Z, Yang R, Lewis J, Bigner D, Zhao F, He Y, Yan H, Shen Q, Zhang L. Xu C, et al. Among authors: wang z, wang y. Oncotarget. 2017 Jul 28;8(44):76644-76655. doi: 10.18632/oncotarget.19656. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100338 Free PMC article.
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