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Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.
Dowling JE, Chuaqui C, Pontz TW, Lyne PD, Larsen NA, Block MH, Chen H, Su N, Wu A, Russell D, Pollard H, Lee JW, Peng B, Thakur K, Ye Q, Zhang T, Brassil P, Racicot V, Bao L, Denz CR, Cooke E. Dowling JE, et al. Among authors: cooke e. ACS Med Chem Lett. 2012 Jan 24;3(4):278-83. doi: 10.1021/ml200257n. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900464 Free PMC article.
Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo.
Dowling JE, Alimzhanov M, Bao L, Block MH, Chuaqui C, Cooke EL, Denz CR, Hird A, Huang S, Larsen NA, Peng B, Pontz TW, Rivard-Costa C, Saeh JC, Thakur K, Ye Q, Zhang T, Lyne PD. Dowling JE, et al. Among authors: cooke el. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5. doi: 10.1021/ml400197u. eCollection 2013 Aug 8. ACS Med Chem Lett. 2013. PMID: 24900749 Free PMC article.
Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases.
Gingipalli L, Block MH, Bao L, Cooke E, Dakin LA, Denz CR, Ferguson AD, Johannes JW, Larsen NA, Lyne PD, Pontz TW, Wang T, Wu X, Wu A, Zhang HJ, Zheng X, Dowling JE, Lamb ML. Gingipalli L, et al. Among authors: cooke e. Bioorg Med Chem Lett. 2018 May 1;28(8):1336-1341. doi: 10.1016/j.bmcl.2018.03.018. Epub 2018 Mar 7. Bioorg Med Chem Lett. 2018. PMID: 29559278
Factors Associated with Shock at Presentation in Kawasaki Disease Versus Multisystem Inflammatory Syndrome in Children Associated with COVID-19.
Jain SS, Harahsheh AS, Lee S, Raghuveer G, Dahdah N, Khoury M, Portman MA, Wehrmann M, Sabati AA, Fabi M, Thacker D, Misra N, Hicar MD, Choueiter NF, Elias MD, Dionne A, Orr WB, Szmuszkovicz JR, Tierney SS, Garrido-Garcia LM, Dallaire F, Sundaram B, Prasad D, Harris TH, Braunlin E, Cooke EF, Manlhiot C, Farid P, McCrindle BW; International Kawasaki Disease Registry. Jain SS, et al. Among authors: cooke ef. Can J Cardiol. 2024 Nov 30:S0828-282X(24)01233-9. doi: 10.1016/j.cjca.2024.11.027. Online ahead of print. Can J Cardiol. 2024. PMID: 39622342 Free article.
Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).
Bellos E, Santillo D, Vantourout P, Jackson HR, Duret A, Hearn H, Seeleuthner Y, Talouarn E, Hodeib S, Patel H, Powell O, Yeoh S, Mustafa S, Habgood-Coote D, Nichols S, Estramiana Elorrieta L, D'Souza G, Wright VJ, Estrada-Rivadeneyra D, Tremoulet AH, Dummer KB, Netea SA, Condino-Neto A, Lau YL, Núñez Cuadros E, Toubiana J, Holanda Pena M, Rieux-Laucat F, Luyt CE, Haerynck F, Mège JL, Chakravorty S, Haddad E, Morin MP, Metin Akcan Ö, Keles S, Emiroglu M, Alkan G, Tüter Öz SK, Elmas Bozdemir S, Morelle G, Volokha A, Kendir-Demirkol Y, Sözeri B, Coskuner T, Yahsi A, Gulhan B, Kanik-Yuksek S, Bayhan GI, Ozkaya-Parlakay A, Yesilbas O, Hatipoglu N, Ozcelik T, Belot A, Chopin E, Barlogis V, Sevketoglu E, Menentoglu E, Gayretli Aydin ZG, Bloomfield M, AlKhater SA, Cyrus C, Stepanovskiy Y, Bondarenko A, Öz FN, Polat M, Fremuth J, Lebl J, Geraldo A, Jouanguy E; COVID-19 Human Genetic Effort; DIAMONDS; EUCLIDS; Carter MJ, Wellman P, Peters M, Pérez de Diego R, Edwards LA, Chiu C, Noursadeghi M, Bolze A, Shimizu C, Kaforou M, Hamilton MS, Herberg JA, Schmitt EG, Rodriguez-Palmero A, Pujol A, Kim J, Cobat A, Abel L, Zhang SY, Casanova JL, Kuijpers TW, Burns JC, Levin M, Hayday AC, Sancho-Shim… See abstract for full author list ➔ Bellos E, et al. J Exp Med. 2024 Dec 2;221(12):e20240699. doi: 10.1084/jem.20240699. Epub 2024 Nov 22. J Exp Med. 2024. PMID: 39576310 Free PMC article.
Artificial Intelligence in European Medicines Regulation: From Vision to Action. Harnessing the Capabilities of Artificial Intelligence for the Benefit of Public and Animal Health.
Correia Pinheiro L, Arlett P, Roes K, Musuamba Tshinanu F, Westman G, Frias Z, Hamann H, Berenguer Jornet J, Khan I, Larsen J, Broich K, Cooke E. Correia Pinheiro L, et al. Among authors: cooke e. Clin Pharmacol Ther. 2024 Nov 22. doi: 10.1002/cpt.3494. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 39574375 No abstract available.
Rfam 15: RNA families database in 2025.
Ontiveros-Palacios N, Cooke E, Nawrocki EP, Triebel S, Marz M, Rivas E, Griffiths-Jones S, Petrov AI, Bateman A, Sweeney B. Ontiveros-Palacios N, et al. Among authors: cooke e. Nucleic Acids Res. 2024 Nov 11:gkae1023. doi: 10.1093/nar/gkae1023. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39526405
To Biopsy or Not to Biopsy: A Retroperitoneal Mass.
Assani K, Cole MW, Nable MM, Launer BM, Tosoian JJ, Cooke EA, Kavoussi NL. Assani K, et al. Among authors: cooke ea. Urology. 2024 Nov 1:S0090-4295(24)00957-9. doi: 10.1016/j.urology.2024.10.061. Online ahead of print. Urology. 2024. PMID: 39489382 No abstract available.
437 results