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VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection.
Di Bisceglie AM, Sulkowski M, Gane E, Jacobson IM, Nelson D, DeSouza C, Alves K, George S, Kieffer T, Zhang EZ, Kauffman R, Asmal M, Koziel MJ. Di Bisceglie AM, et al. Among authors: jacobson im. Eur J Gastroenterol Hepatol. 2014 Jul;26(7):761-73. doi: 10.1097/MEG.0000000000000084. Eur J Gastroenterol Hepatol. 2014. PMID: 24901821 Clinical Trial.
A randomized trial of pegylated interferon alpha-2b plus ribavirin in the retreatment of chronic hepatitis C.
Jacobson IM, Gonzalez SA, Ahmed F, Lebovics E, Min AD, Bodenheimer HC Jr, Esposito SP, Brown RS Jr, Bräu N, Klion FM, Tobias H, Bini EJ, Brodsky N, Cerulli MA, Aytaman A, Gardner PW, Geders JM, Spivack JE, Rahmin MG, Berman DH, Ehrlich J, Russo MW, Chait M, Rovner D, Edlin BR. Jacobson IM, et al. Am J Gastroenterol. 2005 Nov;100(11):2453-62. doi: 10.1111/j.1572-0241.2005.00282.x. Am J Gastroenterol. 2005. PMID: 16279900 Clinical Trial.
Future therapies for hepatitis C: where do we go from here?
Sigal S, Jacobson I. Sigal S, et al. Nat Clin Pract Gastroenterol Hepatol. 2007 Feb;4(2):60-1. doi: 10.1038/ncpgasthep0736. Nat Clin Pract Gastroenterol Hepatol. 2007. PMID: 17268539 No abstract available.
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.
Kuntzen T, Timm J, Berical A, Lennon N, Berlin AM, Young SK, Lee B, Heckerman D, Carlson J, Reyor LL, Kleyman M, McMahon CM, Birch C, Schulze Zur Wiesch J, Ledlie T, Koehrsen M, Kodira C, Roberts AD, Lauer GM, Rosen HR, Bihl F, Cerny A, Spengler U, Liu Z, Kim AY, Xing Y, Schneidewind A, Madey MA, Fleckenstein JF, Park VM, Galagan JE, Nusbaum C, Walker BD, Lake-Bakaar GV, Daar ES, Jacobson IM, Gomperts ED, Edlin BR, Donfield SM, Chung RT, Talal AH, Marion T, Birren BW, Henn MR, Allen TM. Kuntzen T, et al. Among authors: jacobson im. Hepatology. 2008 Dec;48(6):1769-78. doi: 10.1002/hep.22549. Hepatology. 2008. PMID: 19026009 Free PMC article.
219 results