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Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kubacka M, Mogilski S, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: wasik a. Neuropharmacology. 2014 Oct;85:253-62. doi: 10.1016/j.neuropharm.2014.05.036. Epub 2014 Jun 4. Neuropharmacology. 2014. PMID: 24905144
Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.
Partyka A, Chłoń-Rzepa G, Wasik A, Jastrzębska-Więsek M, Bucki A, Kołaczkowski M, Satała G, Bojarski AJ, Wesołowska A. Partyka A, et al. Among authors: wasik a. Bioorg Med Chem. 2015 Jan 1;23(1):212-21. doi: 10.1016/j.bmc.2014.11.008. Epub 2014 Nov 11. Bioorg Med Chem. 2015. PMID: 25435254
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Kołaczkowski M, Marcinkowska M, Bucki A, Śniecikowska J, Pawłowski M, Kazek G, Siwek A, Jastrzębska-Więsek M, Partyka A, Wasik A, Wesołowska A, Mierzejewski P, Bienkowski P. Kołaczkowski M, et al. Among authors: wasik a. Eur J Med Chem. 2015 Mar 6;92:221-35. doi: 10.1016/j.ejmech.2014.12.045. Epub 2014 Dec 24. Eur J Med Chem. 2015. PMID: 25557493
Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats.
Jastrzębska-Więsek M, Siwek A, Partyka A, Szewczyk B, Sowa-Kućma M, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: wasik a. Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1079-88. doi: 10.1007/s00210-015-1141-2. Epub 2015 Jun 16. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26077660
ADN-1184, a monoaminergic ligand with 5-HT6/7 receptor antagonist action, exhibits activity in animal models of anxiety.
Partyka A, Wasik A, Jastrzębska-Więsek M, Mierzejewski P, Bieńkowski P, Kołaczkowski M, Wesołowska A. Partyka A, et al. Among authors: wasik a. Naunyn Schmiedebergs Arch Pharmacol. 2016 Jun;389(6):593-602. doi: 10.1007/s00210-016-1229-3. Epub 2016 Mar 16. Naunyn Schmiedebergs Arch Pharmacol. 2016. PMID: 26979176 Free PMC article.
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Kołaczkowski M, Marcinkowska M, Bucki A, Pawłowski M, Mitka K, Jaśkowska J, Kowalski P, Kazek G, Siwek A, Wasik A, Wesołowska A, Mierzejewski P, Bienkowski P. Kołaczkowski M, et al. Among authors: wasik a. J Med Chem. 2014 Jun 12;57(11):4543-57. doi: 10.1021/jm401895u. Epub 2014 May 23. J Med Chem. 2014. PMID: 24805037
253 results