Singh NS - Search Results

1

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

Paul RK, Singh NS, Khadeer M, Moaddel R, Sanghvi M, Green CE, O'Loughlin K, Torjman MC, Bernier M, Wainer IW. Paul RK, et al. Among authors: singh ns. Anesthesiology. 2014 Jul;121(1):149-59. doi: 10.1097/ALN.0000000000000285. Anesthesiology. 2014. PMID: 24936922 Free PMC article.

2

Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats.

Moaddel R, Sanghvi M, Ramamoorthy A, Jozwiak K, Singh N, Green C, O'Loughlin K, Torjman M, Wainer IW. Moaddel R, et al. J Pharm Biomed Anal. 2016 Aug 5;127:3-8. doi: 10.1016/j.jpba.2016.03.030. Epub 2016 Mar 14. J Pharm Biomed Anal. 2016. PMID: 27017097 Free PMC article.

3

Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells.

Singh NS, Paul RK, Ramamoorthy A, Torjman MC, Moaddel R, Bernier M, Wainer IW. Singh NS, et al. Cell Signal. 2013 Dec;25(12):2634-45. doi: 10.1016/j.cellsig.2013.08.025. Epub 2013 Sep 4. Cell Signal. 2013. PMID: 24012499 Free PMC article.

4

What is hydroxynorketamine and what can it bring to neurotherapeutics?

Singh NS, Zarate CA Jr, Moaddel R, Bernier M, Wainer IW. Singh NS, et al. Expert Rev Neurother. 2014 Nov;14(11):1239-42. doi: 10.1586/14737175.2014.971760. Expert Rev Neurother. 2014. PMID: 25331415 Free PMC article.

5

Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells.

Singh NS, Rutkowska E, Plazinska A, Khadeer M, Moaddel R, Jozwiak K, Bernier M, Wainer IW. Singh NS, et al. PLoS One. 2016 Apr 20;11(4):e0149499. doi: 10.1371/journal.pone.0149499. eCollection 2016. PLoS One. 2016. PMID: 27096720 Free PMC article.

6

Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity.

Singh NS, Paul RK, Sichler M, Moaddel R, Bernier M, Wainer IW. Singh NS, et al. Anal Biochem. 2012 Feb 15;421(2):460-6. doi: 10.1016/j.ab.2011.10.003. Epub 2011 Oct 10. Anal Biochem. 2012. PMID: 22037294 Free PMC article.

7

Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells.

Singh NS, Paul RK, Torjman MC, Wainer IW. Singh NS, et al. Neurosci Lett. 2013 Feb 22;535:90-4. doi: 10.1016/j.neulet.2012.12.024. Epub 2012 Dec 27. Neurosci Lett. 2013. PMID: 23274708 Free PMC article.

8

Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells.

Wnorowski A, Sadowska M, Paul RK, Singh NS, Boguszewska-Czubara A, Jimenez L, Abdelmohsen K, Toll L, Jozwiak K, Bernier M, Wainer IW. Wnorowski A, et al. Among authors: singh ns. Cell Signal. 2015 May;27(5):997-1007. doi: 10.1016/j.cellsig.2015.02.012. Epub 2015 Feb 20. Cell Signal. 2015. PMID: 25703025 Free PMC article.

9

Enantioselective inhibition of d-serine transport by (S)-ketamine.

Singh NS, Bernier M, Camandola S, Khadeer MA, Moaddel R, Mattson MP, Wainer IW. Singh NS, et al. Br J Pharmacol. 2015 Sep;172(18):4546-4559. doi: 10.1111/bph.13239. Epub 2015 Jul 31. Br J Pharmacol. 2015. PMID: 26140427 Free PMC article.

10

NMDAR inhibition-independent antidepressant actions of ketamine metabolites.

Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA Jr, Gould TD. Zanos P, et al. Among authors: singh ns. Nature. 2016 May 26;533(7604):481-6. doi: 10.1038/nature17998. Epub 2016 May 4. Nature. 2016. PMID: 27144355 Free PMC article.

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