Davies P - Search Results

1

Pharmacological profile of the substituted beta-lactam L-659,286: a member of a new class of human PMN elastase inhibitors.

Bonney RJ, Ashe B, Maycock A, Dellea P, Hand K, Osinga D, Fletcher D, Mumford R, Davies P, Frankenfield D, et al. Bonney RJ, et al. Among authors: davies p. J Cell Biochem. 1989 Jan;39(1):47-53. doi: 10.1002/jcb.240390106. J Cell Biochem. 1989. PMID: 2497109

2

Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.

Finke PE, Shah SK, Ashe BM, Ball RG, Blacklock TJ, Bonney RJ, Brause KA, Chandler GO, Cotton M, Davies P, et al. Finke PE, et al. Among authors: davies p. J Med Chem. 1992 Oct 16;35(21):3731-44. doi: 10.1021/jm00099a002. J Med Chem. 1992. PMID: 1433188

3

The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase.

Davies P, Ashe BM, Bonney RJ, Dorn C, Finke P, Fletcher D, Hanlon WA, Humes JL, Maycock A, Mumford RA, et al. Davies P, et al. Ann N Y Acad Sci. 1991;624:219-29. doi: 10.1111/j.1749-6632.1991.tb17021.x. Ann N Y Acad Sci. 1991. PMID: 2064223 Review. No abstract available.

4

The in vitro and in vivo recovery of PMN elastase:beta-lactam inhibitor complexes by cation exchange chromatography.

Opas EE, Dellea PS, Fletcher DS, Davies P, Humes JL. Opas EE, et al. Among authors: davies p. Ann N Y Acad Sci. 1991;624:348-9. doi: 10.1111/j.1749-6632.1991.tb17044.x. Ann N Y Acad Sci. 1991. PMID: 2064243 No abstract available.

5

A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster.

Fletcher DS, Osinga DG, Hand KM, Dellea PS, Ashe BM, Mumford RA, Davies P, Hagmann W, Finke PE, Doherty JB, et al. Fletcher DS, et al. Among authors: davies p. Am Rev Respir Dis. 1990 Mar;141(3):672-7. doi: 10.1164/ajrccm/141.3.672. Am Rev Respir Dis. 1990. PMID: 2310097

6

An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.

Fletcher DS, Osinga DG, Keenan K, Bonney RJ, Doherty JB, Finke PE, Shah SK, Davies P. Fletcher DS, et al. Among authors: davies p. J Pharmacol Exp Ther. 1995 Jul;274(1):548-54. J Pharmacol Exp Ther. 1995. PMID: 7616444

7

rTNF alpha facilitates human polymorphonuclear leukocyte adherence to fibrinogen matrices with mobilization of specific and tertiary but not azurophilic granule markers.

Hanlon WA, Stolk J, Davies P, Humes JL, Mumford R, Bonney RJ. Hanlon WA, et al. Among authors: davies p. J Leukoc Biol. 1991 Jul;50(1):43-8. doi: 10.1002/jlb.50.1.43. J Leukoc Biol. 1991. PMID: 1647433

8

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters.

Doherty JB, Ashe BM, Barker PL, Blacklock TJ, Butcher JW, Chandler GO, Dahlgren ME, Davies P, Dorn CP Jr, Finke PE, et al. Doherty JB, et al. Among authors: davies p. J Med Chem. 1990 Sep;33(9):2513-21. doi: 10.1021/jm00171a028. J Med Chem. 1990. PMID: 2391691

9

Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to characterize inhibitors of polymorphonuclear leukocyte elastase.

Pacholok SG, Davies P, Dorn C, Finke P, Hanlon WA, Mumford RA, Humes JL. Pacholok SG, et al. Among authors: davies p. Biochem Pharmacol. 1995 May 17;49(10):1513-20. doi: 10.1016/0006-2952(95)00031-t. Biochem Pharmacol. 1995. PMID: 7763294

10

Purification and characterization by fast-atom-bombardment mass spectrometry of the polymorphonuclear-leucocyte-elastase-generated A alpha (1-21) fragment of fibrinogen from human blood after incubation with calcium ionophore A23187.

Dewey RS, Liesch JM, Williams HR, Sugg EE, Dolan CA, Davies P, Mumford RA, Albers-Schönberg G. Dewey RS, et al. Among authors: davies p. Biochem J. 1992 Jan 15;281 ( Pt 2)(Pt 2):519-24. doi: 10.1042/bj2810519. Biochem J. 1992. PMID: 1736899 Free PMC article.

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