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Page 1
Ectosomes: a new mechanism for non-exosomal secretion of tau protein.
Dujardin S, Bégard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas MC, Bousset L, Melki R, Aurégan G, Hantraye P, Brouillet E, Buée L, Colin M. Dujardin S, et al. Among authors: lachaud c. PLoS One. 2014 Jun 27;9(6):e100760. doi: 10.1371/journal.pone.0100760. eCollection 2014. PLoS One. 2014. PMID: 24971751 Free PMC article.
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies.
Dujardin S, Lécolle K, Caillierez R, Bégard S, Zommer N, Lachaud C, Carrier S, Dufour N, Aurégan G, Winderickx J, Hantraye P, Déglon N, Colin M, Buée L. Dujardin S, et al. Among authors: lachaud c. Acta Neuropathol Commun. 2014 Jan 30;2:14. doi: 10.1186/2051-5960-2-14. Acta Neuropathol Commun. 2014. PMID: 24479894 Free PMC article.
Different tau species lead to heterogeneous tau pathology propagation and misfolding.
Dujardin S, Bégard S, Caillierez R, Lachaud C, Carrier S, Lieger S, Gonzalez JA, Deramecourt V, Déglon N, Maurage CA, Frosch MP, Hyman BT, Colin M, Buée L. Dujardin S, et al. Among authors: lachaud c. Acta Neuropathol Commun. 2018 Nov 29;6(1):132. doi: 10.1186/s40478-018-0637-7. Acta Neuropathol Commun. 2018. PMID: 30497516 Free PMC article.
Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?
Moreau C, Danel V, Devedjian JC, Grolez G, Timmerman K, Laloux C, Petrault M, Gouel F, Jonneaux A, Dutheil M, Lachaud C, Lopes R, Kuchcinski G, Auger F, Kyheng M, Duhamel A, Pérez T, Pradat PF, Blasco H, Veyrat-Durebex C, Corcia P, Oeckl P, Otto M, Dupuis L, Garçon G, Defebvre L, Cabantchik ZI, Duce J, Bordet R, Devos D. Moreau C, et al. Among authors: lachaud c. Antioxid Redox Signal. 2018 Sep 10;29(8):742-748. doi: 10.1089/ars.2017.7493. Epub 2018 Feb 8. Antioxid Redox Signal. 2018. PMID: 29287521 Free PMC article. Clinical Trial.
LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype.
Cobo-Vuilleumier N, Rodríguez-Fernandez S, López-Noriega L, Lorenzo PI, Franco JM, Lachaud CC, Vazquez EM, Legido RA, Dorronsoro A, López-Férnandez-Sobrino R, Fernández-Santos B, Serrano CE, Salas-Lloret D, van Overbeek N, Ramos-Rodriguez M, Mateo-Rodríguez C, Hidalgo L, Marin-Canas S, Nano R, Arroba AI, Caro AC, Vertegaal AC, Montalvo AM, Martín F, Aguilar-Diosdado M, Piemonti L, Pasquali L, Prieto RG, Sánchez MIG, Eizirik DL, Martínez-Brocca MA, Vives-Pi M, Gauthier BR. Cobo-Vuilleumier N, et al. Among authors: lachaud cc. Clin Transl Med. 2024 Dec;14(12):e70134. doi: 10.1002/ctm2.70134. Clin Transl Med. 2024. PMID: 39702941 Free PMC article.
Heterozygous RPA2 variant as a novel genetic cause of telomere biology disorders.
Kochman R, Ba I, Yates M, Pirabakaran V, Gourmelon F, Churikov D, Laffaille M, Kermasson L, Hamelin C, Marois I, Jourquin F, Braud L, Bechara M, Lainey E, Nunes H, Breton P, Penhouet M, David P, Géli V, Lachaud C, Maréchal A, Revy P, Kannengiesser C, Saintomé C, Coulon S. Kochman R, et al. Among authors: lachaud c. Genes Dev. 2024 Sep 19;38(15-16):755-771. doi: 10.1101/gad.352032.124. Genes Dev. 2024. PMID: 39231615 Free PMC article.
mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.
Lipskaia L, Breau M, Cayrou C, Churikov D, Braud L, Jacquet J, Born E, Fouillade C, Curras-Alonso S, Bauwens S, Jourquin F, Fiore F, Castellano R, Josselin E, Sánchez-Ferrer C, Giovinazzo G, Lachaud C, Gilson E, Flores I, Londono-Vallejo A, Adnot S, Géli V. Lipskaia L, et al. Among authors: lachaud c. EMBO Rep. 2024 Mar;25(3):1650-1684. doi: 10.1038/s44319-023-00041-1. Epub 2024 Feb 29. EMBO Rep. 2024. PMID: 38424230 Free PMC article.
STIM1 translocation to the nucleus protects cells from DNA damage.
Sanchez-Lopez I, Orantos-Aguilera Y, Pozo-Guisado E, Alvarez-Barrientos A, Lilla S, Zanivan S, Lachaud C, Martin-Romero FJ. Sanchez-Lopez I, et al. Among authors: lachaud c. Nucleic Acids Res. 2024 Mar 21;52(5):2389-2415. doi: 10.1093/nar/gkae001. Nucleic Acids Res. 2024. PMID: 38224453 Free PMC article.
62 results